Autophagy: cancer's friend or foe?
The functional relevance of autophagy in tumor formation and progression remains
controversial. Autophagy can promote tumor suppression during cancer initiation and …
controversial. Autophagy can promote tumor suppression during cancer initiation and …
[HTML][HTML] Molecular modulation of autophagy: New venture to target resistant cancer stem cells
HK Mandhair, M Arambasic, U Novak… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Autophagy is a highly regulated catabolic process in which superfluous, damaged
organelles and other cytoplasmic constituents are delivered to the lysosome for clearance …
organelles and other cytoplasmic constituents are delivered to the lysosome for clearance …
Targeting cancer cells through autophagy for anticancer therapy
S Turcotte, AJ Giaccia - Current opinion in cell biology, 2010 - Elsevier
Autophagy is a cellular degradation process in which portions of the cell's cytoplasm and
organelles are sequestered in a double-membrane bound vesicle called an …
organelles are sequestered in a double-membrane bound vesicle called an …
Autophagy modulation as a target for anticancer drug discovery
X Li, H Xu, Y Liu, N An, S Zhao, J Bao - Acta Pharmacologica Sinica, 2013 - nature.com
Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
Autophagy and autophagy-related pathways in cancer
Maintenance of protein homeostasis and organelle integrity and function is critical for
cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates …
cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates …
Molecular pathways: autophagy in cancer—a matter of timing and context
M Cicchini, V Karantza, B Xia - Clinical cancer research, 2015 - AACR
Autophagy is an intracellular self-digestion mechanism, by which cellular components are
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …
sorted into double-membrane autophagosomes and delivered to lysosomes for degradation …
[HTML][HTML] Unfolding the role of autophagy in the cancer metabolism
Autophagy is considered an indispensable process that scavenges toxins, recycles complex
macromolecules, and sustains the essential cellular functions. In addition to its …
macromolecules, and sustains the essential cellular functions. In addition to its …
Autophagy and cancer: Basic mechanisms and inhibitor development
Y Hama, Y Ogasawara, NN Noda - Cancer Science, 2023 - Wiley Online Library
Autophagy is a lysosomal degradation system of cytoplasmic components that contributes to
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …
cellular homeostasis through the turnover of various biomolecules and organelles, often in a …
Autophagy: an emerging target for cancer therapy
M Høyer-Hansen, M Jäättelä - Autophagy, 2008 - Taylor & Francis
Macroautophagy (hereafter referred to as autophagy) is a lysosomal catabolic pathway
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …
Autophagy and tumorigenesis
M Rangel, J Kong, V Bhatt, K Khayati… - The FEBS …, 2022 - Wiley Online Library
Autophagy is a catabolic process that captures cellular waste and degrades them in the
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …
lysosome. The main functions of autophagy are quality control of cytosolic proteins and …