The immunology of human hookworm infections

HJ McSorley, A Loukas - Parasite immunology, 2010 - Wiley Online Library
Hookworms are one of the most prevalent parasites of humans in developing countries, but
we know relatively little about the immune response generated to hookworm infection. This …

Comparative immunology of human and animal models of hookworm infection

RT Fujiwara, SM Geiger, J Bethony… - Parasite …, 2006 - Wiley Online Library
Hookworm infection is a major cause of disease burden for animals and humans. Over the
past years, the use of animal models in hookworm infections has been driven by the search …

Immunobiology of hookworm infection

A Loukas, SL Constant… - FEMS Immunology & …, 2005 - academic.oup.com
Hookworms infect almost one billion people and are a major cause of iron-deficiency
anaemia in developing countries of the tropics. Despite their prevalence and the morbidity …

[HTML][HTML] Human hookworm infection in the 21st century

S Brooker, J Bethony, PJ Hotez - Advances in parasitology, 2004 - ncbi.nlm.nih.gov
The scientific study of human hookworm infection began at the dawn of the twentieth
century. In recent years, there have been dramatic improvements in our understanding of …

Immunology of experimental and natural human hookworm infection

S Gaze, JM Bethony, MV Periago - Parasite immunology, 2014 - Wiley Online Library
Human hookworm infection is one amongst the most prevalent of the neglected tropical
diseases. An informative experimental animal model, that is, one that parallels a human …

The immunoepidemiology of human hookworm infection

RJ Quinnell, J Bethony, DI Pritchard - Parasite immunology, 2004 - Wiley Online Library
Advances in hookworm immunoepidemiology are reviewed. Recent studies demonstrate a
mixed Th1/Th2 response in human hookworm infection, with immunosuppression of specific …

Immune responses in hookworm infections

A Loukas, P Prociv - Clinical microbiology reviews, 2001 - Am Soc Microbiol
Hookworms infect perhaps one-fifth of the entire human population, yet little is known about
their interaction with our immune system. The two major species are Necator americanus …

Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative

PJ Hotez, B Zhan, JM Bethony, A Loukas… - International journal for …, 2003 - Elsevier
Hookworm infection is one of the most important parasitic infections of humans, possibly
outranked only by malaria as a cause of misery and suffering. An estimated 1.2 billion …

Twenty-first century progress toward the global control of human hookworm infection

R Bungiro, M Cappello - Current Infectious Disease Reports, 2011 - Springer
Hookworms are bloodsucking nematodes that afflict up to 740 million persons in tropical and
subtropical regions, with Asia and sub-Saharan Africa exhibiting particularly high infection …

Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines

MS Pearson, L Tribolet, C Cantacessi… - Journal of allergy and …, 2012 - Elsevier
Hookworms produce a vast repertoire of structurally and functionally diverse molecules that
mediate their long-term survival and pathogenesis within a human host. Many of these …