Hematopoietic stem cells (HSCs) are defined by the capabilities of multi-lineage
differentiation and long-term self-renewal. Both these characteristics contribute to maintain …

Hematopoietic stem cells (HSCs) can be isolated from murine bone marrow by their ability to
efflux the Hoechst 33342 dye. This method defines an extremely small and …

Hematopoietic stem cells (HSCs) primarily reside in bone marrow, are defined by their ability
to maintain blood homeostasis, and replenish themselves through self‐renewal. Although …

The field of hematopoietic stem cell (HSC) biology has become increasingly dominated by
the pursuit and study of highly purified populations of HSCs. Such HSCs are typically …

In the mouse, over the last 20 years, a set of cell‐surface markers and activities have been
identified, enabling the isolation of bone marrow (BM) populations highly enriched in …

Hematopoietic stem cells (HSCs) have the capacity to self‐renew and the potential to
differentiate into all of the mature blood cell types. The ability to prospectively identify and …

Hematopoietic stem cells (HSCs) remain by far the most well‐characterized adult stem cell
population both in terms of markers for purification and assays to assess functional potential …

Considerable efforts have been made in recent years in understanding the mechanisms that
govern hematopoietic stem cell (HSC) origin, development, differentiation, self-renewal …

The ability to highly purify and characterize hematopoietic stem cells (HSC) from mice and
humans has opened up an exceedingly rich field of basic science research with enormous …

The side population (SP) is a subpopulation of mouse bone marrow cells highly enriched for
hematopoietic stem cell activity. The SP is identified using flow cytometry as a minor …