Coronaviruses encode a variable number of accessory proteins that are involved in host-
virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 …

Antiviral signaling, immune response and cell metabolism are dysregulated by SARS‐CoV‐
2, the causative agent of COVID‐19. Here, we show that SARS‐CoV‐2 accessory proteins …

The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative
genomic approaches, an additional accessory protein, ORF3c, has been predicted to be …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses high
amounts of the protein Orf9b to target the mitochondrial outer membrane protein Tom70 …

Virus infection involves the manipulation of key host cell functions by specialized virulence
proteins. The Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) small …

In a recent Perspective article in Nature Reviews Immunology (Wong, LY. R. & Perlman, S.
Immune dysregulation and immunopathology induced by SARS-CoV-2 and related …

The emergence of the COVID-19 pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), remains a great threat to global health. ORF9b, an important …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF3a protein plays a vital
role in viral pathogenesis and coronavirus disease 2019 (COVID-19). Like the spike protein …

Recently in an editorial published as an “early view” paper in the European Respiratory
Journal, Hartsell et al.[1] reported that ORF8a has a role in SARS-CoV-2 infection. In figure …

The accessory protein ORF3a, from SARS-CoV-2, plays a critical role in viral infection and
pathogenesis. Here, we characterized ORF3a assembly, ion channel activity, subcellular …