CpG oligodeoxynucleotides adsorbed onto polylactide-co-glycolide microparticles improve the immunogenicity and protective activity of the licensed anthrax vaccine

H Xie, I Gursel, BE Ivins, M Singh… - Infection and …, 2005 - Am Soc Microbiol
To reduce the biothreat posed by anthrax, efforts are under way to improve the protection
afforded by vaccination. This work examines the ability of immunostimulatory CpG …

Mucosal immunogenicity elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly (D, L-lactide-co-glycolide) microspheres

K Allaoui-Attarki, E Fattal, S Pecquet, S Trollé… - Vaccine, 1998 - Elsevier
Poly (d, l-lactide-co-glycolide) microspheres loaded with phosphorylcholine linked to
thyroglobulin (PC-Thyr) as protein carrier were prepared. The entrapment efficiency reached …

Diphtheria toxoid loaded poly-(ε-caprolactone) nanoparticles as mucosal vaccine delivery systems

J Singh, S Pandit, VW Bramwell, HO Alpar - Methods, 2006 - Elsevier
Poly-(ε-caprolactone)(PCL), a poly (lactide-co-glycolide)(PLGA)-PCL blend and co-polymer
nanoparticles encapsulating diphtheria toxoid (DT) were investigated for their potential as a …

Allergen‐loaded biodegradable poly(d,l‐lactic‐co‐glycolic) acid nanoparticles down‐regulate an ongoing Th2 response in the BALB/c mouse model

I Schöll, A Weissenböck… - Clinical & …, 2004 - Wiley Online Library
Background and objective Biocompatible and biodegradable microparticles have gained
interest as antigen delivery systems during the recent years. We investigated whether …

Modulation of the specific allergic response by mite allergens encapsulated into liposomes

L Calderón, E Facenda, L Machado, K Uyema… - Vaccine, 2006 - Elsevier
Liposomes are non toxic and biodegradable lipid vesicles, which are safe and effective
adjuvants to induce Th1-skewed immune response. Therefore, the encapsulation of …

Microparticles for intranasal immunization

M Vajdy, DT O'Hagan - Advanced drug delivery reviews, 2001 - Elsevier
Of the several routes available for mucosal immunization, the nasal route is particularly
attractive because of ease of administration and the induction of potent immune responses …

Peptide/protein vaccine delivery system based on PLGA particles

M Allahyari, E Mohit - Human vaccines & immunotherapeutics, 2016 - Taylor & Francis
abstract Due to the excellent safety profile of poly (D, L-lactide-co-glycolide)(PLGA) particles
in human, and their biodegradability, many studies have focused on the application of PLGA …

Comparison of the effects of various fine particles on IgE antibody production in mice inhaling Japanese cedar pollen allergens

K Maejima, K Tamura, Y Taniguchi… - Journal of toxicology …, 1997 - Taylor & Francis
The adjuvant effects of various fine particles [Kanto loam dust, fly ash, carbon black, diesel
exhaust particles (DEP), and aluminum hydroxide (alum)] on immunoglobulin E (IgE) …

Alginate microparticles loaded with lipopolysaccharide subunit antigen for mucosal vaccination against Klebsiella pneumoniae

RR Jain, MR Mehta, AR Bannalikar, MD Menon - Biologicals, 2015 - Elsevier
Klebsiella pneumoniae (K. pneumoniae) is one of the commonest causes of nosocomial
infections in human beings. Since K. pneumoniae infections are air borne type, controlling it …

Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally

KS Jaganathan, SP Vyas - Vaccine, 2006 - Elsevier
Surface-modified dl-lactide/glycolide copolymer (PLGA) microspheres with chitosan (CS)
were developed for nasal immunization using recombinant Hepatitis B (HBsAg) surface …