Rheumatic heart disease represents a leading cause of mortality caused by Group A
Streptococcus (GAS) infections transmitted through the respiratory route. Although GAS …

Background Allergic asthma is caused by abnormal immunoreactivity against allergens such
as house dust mites among which Dermatophagoides farinae (Der f) is a common species …

Background: Selected lactic acid bacteria were reported to prevent atopic dermatitis and
experimental asthma but the mechanisms of their immunomodulatory effects are not fully …

Background More than 90% of house dust mite‐allergic patients are sensitized to the major
D ermatophagoides pteronyssinus allergen, D er p 2. The aim of this study was to develop …

In this study, the efficacy of mucoadhesive polymers, ie, chitosan and glycol chitosan as a
mucoadhesive coating material in nasal vaccine delivery was investigated. The Hepatitis B …

Herein we describe a formulation of self-encapsulating poly (lactic-co-glycolic acid)(PLGA)
microspheres for vaccine delivery. Self-healing encapsulation is a novel encapsulation …

We have evaluated the ability of recombinant E2 antigen, as a surfactant free formulation of
poly (d, l-lactide-co-glycolide)(PLGA) microspheres, to elicit a systemic immune response …

CTL responses play a critical role in clearing viral infections. We have investigated the
potential of poly (lactide-co-glycolide)(PLG) microparticles as an oral delivery system for …

Designing strategies for targeting antigens to dendritic cells is a major goal in vaccinology.
Here, PLGA (poly lactic-co-glycolic acid) microspheres and with several surface …

Liposome–protamine–DNA nanoparticles (LPD) are safe, effective, and non-toxic adjuvants
that induce Th1-like immune responses. We hypothesized that encapsulation of allergens …