Fixed combination of amlodipine/atorvastatin: from mechanisms to trials

B Ivanovic, M Tadic - Journal of cardiovascular …, 2013 - journals.sagepub.com
Cardiovascular diseases are the leading cause of death worldwide. Risk factors are rarely
seen individually, and the 2 most common and most frequently associated risk factors are …

Fixed combination of amlodipine and atorvastatin in cardiovascular risk management: patient perspectives

M Devabhaktuni, S Bangalore - Vascular health and risk …, 2009 - Taylor & Francis
Hypertension and dyslipidemia are two of the most commonly co-occurring cardiovascular
risk factors which together cause an increase in coronary heart disease-related events that …

Amlodipine/atorvastatin fixed-dose combination: a review of its use in the prevention of cardiovascular disease and in the treatment of hypertension and dyslipidemia

K McKeage, MAA Siddiqui - American journal of cardiovascular drugs, 2008 - Springer
Amlodipine/atorvastatin (Caduet®) is a once-daily fixed-dose combination of the
dihydropyridine calcium channel antagonist amlodipine and the HMG-CoA reductase …

A single-pill combination of amlodipine besylate and atorvastatin calcium (update).

R Blank, FD Hobbs, J Zamorano… - Drugs of Today …, 2007 - europepmc.org
This review describes the clinical profile and rationale for the development of a single-pill
formulation of the calcium channel blocker amlodipine besylate, a blood-pressure--lowering …

[PDF][PDF] Efficacy and safety of a single-pill combination of atorvastatin/amlodipine in patients with arterial hypertension and dyslipidemia

SN Naydenov, NM Runev, EI Manov… - Acta Clinica …, 2018 - hrcak.srce.hr
The aim was to evaluate the efficacy of a single-pill combination of atorvastatin/amlodipine
in patients with arterial hypertension, dyslipidemia and moderate to high cardiovascular risk …

Amlodipine/atorvastatin: the first cross risk factor polypill for the prevention and treatment of cardiovascular disease

WH Frishman, AL Zuckerman - Expert Review of Cardiovascular …, 2004 - Taylor & Francis
In 2002, the World Health Organization estimated that over 58% of cardiovascular disease in
North America is due to 'both blood pressure and cholesterol higher than optimal' …

A randomized, placebo‐controlled trial to evaluate the efficacy, safety, and pharmacodynamic interaction of coadministered amlodipine and atorvastatin in 1660 …

RA Preston, P Harvey, O Herfert… - The Journal of …, 2007 - Wiley Online Library
Guidelines stress the importance of the simultaneous management of multiple
cardiovascular risk factors. This can in part be achieved by coadministration of lipid …

Efficacy and safety of coadministered amlodipine and atorvastatin in patients with hypertension and dyslipidemia: results of the AVALON trial

FH Messerli, GL Bakris, RD Ferrera… - The Journal of …, 2006 - Wiley Online Library
The AVALON study was a randomized, multicenter trial to assess the efficacy and safety of
coadministered amlodipine and atorvastatin in patients with hypertension and dyslipidemia …

Atorvastatin calcium plus amlodipine for the treatment of hypertension

A Delgado-Montero, JL Zamorano - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Hypertension (HTN) and dyslipemia (DYL) are two of the major modifiable
cardiovascular (CV) risk factors, determinants in the development of cerebrovascular and …

Simultaneous treatment of hypertension and dyslipidaemia may help to reduce overall cardiovascular risk: focus on amlodipine/atorvastatin single‐pill therapy

MR Cowie - International journal of clinical practice, 2005 - Wiley Online Library
Single‐pill amlodipine besylate/atorvastatin calcium (Caduet®, Pfizer Inc, NY, USA) is the
first therapy aimed at the simultaneous treatment of hypertension (HTN) and dyslipidaemia …