Mutational analysis of human T-cell leukemia virus type 2 Tax

TM Ross, AC Minella, ZY Fang, SM Pettiford… - Journal of …, 1997 - Am Soc Microbiol
A mutational analysis of human T-cell leukemia virus type 2 (HTLV-2) Tax (Tax-2) was
performed to identify regions within Tax-2 important for activation of promoters through the …

The tax gene of human T-cell leukemia virus type 2 is essential for transformation of human T lymphocytes

TM Ross, SM Pettiford, PL Green - Journal of virology, 1996 - Am Soc Microbiol
The mechanism of human T-cell leukemia virus (HTLV)-mediated transformation and
induction of malignancy is unknown; however, several studies have implicated the viral …

Activation of Human T-Cell Leukemia Virus Type 1tax Gene Expression in Chronically Infected T Cells

HC Lin, CS Dezzutti, RB Lal, AB Rabson - Journal of virology, 1998 - Am Soc Microbiol
Expression of human T-cell leukemia virus type 1 (HTLV-1) is regulated both by the HTLV-1
Tax transactivator and by cellular transcriptional factors binding to the viral long terminal …

[HTML][HTML] Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 …

AA Franklin, MF Kubik, MN Uittenbogaard… - Journal of Biological …, 1993 - Elsevier
The human T-cell leukemia virus type I (HTLV-I)-encoded transcriptional activator protein
Tax is strongly implicated in HTLV-I pathogenesis. Tax regulates HTLV-I gene expression …

Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activation

F Bex, K Murphy, R Wattiez, A Burny… - Journal of virology, 1999 - Am Soc Microbiol
The Tax transactivator protein of human T-cell leukemia virus type 1 (HTLV-1) plays a
central role in the activation of viral gene expression. In addition, Tax is capable of activating …

Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax

K Endo, A Hirata, K Iwai, M Sakurai, M Fukushi… - Journal of …, 2002 - Am Soc Microbiol
Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 are retroviruses with similar
biological properties. Whereas HTLV-1 is the causative agent of an aggressive T-cell …

[HTML][HTML] Multiple control levels of cell proliferation by human T-cell leukemia virus type 1 Tax protein

JM Mesnard, C Devaux - Virology, 1999 - Elsevier
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of two diseases: adult T-
cell leukemia (ATL), a fatal T-lymphoproliferative disorder, and tropical spastic …

Mechanisms of Tax regulation of human T cell leukemia virus type I gene expression

AA Franklin, JK Nyborg - Journal of Biomedical Science, 1995 - karger.com
During the last several years, the human T cell leukemia virus type I (HTLY-I) has become
recognized as an important cause for public health concern throughout the world. HTLY-I is …

The tax protein from the primate T-cell lymphotropic virus type 3 is expressed in vivo and is functionally related to HTLV-1 Tax rather than HTLV-2 Tax

SA Chevalier, L Meertens, C Pise-Masison, S Calattini… - Oncogene, 2006 - nature.com
Human T-cell leukemia virus and simian T-cell leukemia virus (STLV) form the primate T-cell
lymphotropic viruses group. Human T-cell leukemia virus type 1 and type 2 (HTLV-1 and …

Human T-cell leukemia virus type 1 tax protein activates transcription through AP-1 site by inducing DNA binding activity in T cells

K Iwai, N Mori, M Oie, N Yamamoto, M Fujii - Virology, 2001 - Elsevier
Human T-cell leukemia virus type 1 (HTLV-1) Tax protein induces the expression of various
family members of the transcription factor AP-1, such as c-Jun, JunD, c-Fos, and Fra-1, at the …