Background Gastrointestinal toxicity is frequently observed during radiotherapy of
malignancies in the abdomen and pelvis. The proposed pathophysiology of radiation …

Late gastrointestinal complications of radiation therapy have been recognized but not
extensively studied. In this paper, the late effects of radiation on three gastrointestinal sites …

The frequent use of radiotherapy for abdominal and pelvic malignancies results in an
increased risk of radiation enteritis. An increased understanding of the tissue response and …

Radiation therapy is administered to approximately one third of patients with cancer as part
of their treatment plan. Radiation-induced bowel injury is a major cause of morbidity in these …

With the extended indications for abdominal and pelvic radiation therapy, administered at
higher dosage levels, an increased incidence of radiation injury to the intestine can be …

Possible toxic effects following radiation and chemotherapy of gastrointestinal tumours may
cause a depletion of the mucosal barrier within the radiation volumes with severe mucositis …

Abstract Changes in cancer incidence and mortality have been modest during the past
several decades, but the number of cancer survivors has almost tripled during the same …

The small bowel represents a dose limiting structure for the administration of tumoricidal
abdominal and pelvic doses exceeding 4,500 cGy. If its real incidence remains …

The risk of injury to the intestine is dose limiting during abdominal and pelvic radiation
therapy. Delayed bowel toxicity is difficult to manage and adversely impacts the quality of life …

Ionising radiation therapy is a common treatment modality for different types of cancer and
its use is expected to increase with advances in screening and early detection of cancer …