[HTML][HTML] Severe asthma and the omalizumab option

CWT Miller, N Krishnaswamy, C Johnston… - Clinical and Molecular …, 2008 - Springer
Atopic diseases and asthma are increasing at a remarkable rate on a global scale. It is now
well recognized that asthma is a chronic inflammatory disease of the airways. The …

[HTML][HTML] Omalizumab improves quality of life and asthma control in Chinese patients with moderate to severe asthma: a randomized phase III study

J Li, J Kang, C Wang, J Yang, L Wang… - Allergy, asthma & …, 2016 - synapse.koreamed.org
Purpose Omalizumab is the preferred add-on therapy for patients with moderate-to-severe
persistent allergic asthma and has demonstrated efficacy and safety in various ethnicities …

[HTML][HTML] Omalizumab effectiveness by biomarker status in patients with asthma: evidence from PROSPERO, a prospective real-world study

TB Casale, AT Luskin, W Busse, RS Zeiger… - The Journal of Allergy …, 2019 - Elsevier
Background Omalizumab has demonstrated efficacy in clinical trials of patients with asthma,
but real-world data are needed. Objective To assess outcomes after omalizumab initiation in …

Safety and tolerability of omalizumab

J Corren, TB Casale, B Lanier, R Buhl… - Clinical & …, 2009 - Wiley Online Library
Summary Background Omalizumab (Xolair®) is a recombinant humanized monoclonal anti‐
IgE antibody with proven efficacy in patients with moderate‐to‐severe and severe persistent …

A 26-week, randomized, double-blind, placebo-controlled, multicenter study to evaluate the effect of omalizumab on asthma control in patients with persistent allergic …

J Bardelas, M Figliomeni, F Kianifard, X Meng - Journal of asthma, 2012 - Taylor & Francis
Objective. The 2007 National Heart, Lung, and Blood Institute (NHLBI) asthma guidelines
shifted the focus of care from asthma severity to ongoing assessment of asthma control …

Effects of omalizumab in non-atopic asthma: results from a Spanish multicenter registry

LP de Llano, MC Vennera, FJ Álvarez… - Journal of …, 2013 - Taylor & Francis
Aim. To evaluate the effectiveness of omalizumab in non-atopic asthma. Methods. Using
data from a multicenter registry of severe asthma, we evaluated and compared the clinical …

[HTML][HTML] Baseline asthma burden, comorbidities, and biomarkers in omalizumab-treated patients in PROSPERO

BE Chipps, RS Zeiger, AT Luskin, WW Busse… - Annals of Allergy …, 2017 - Elsevier
Background Patients included in clinical trials do not necessarily reflect the real-world
population. Objective To understand the characteristics, including disease and comorbidity …

[HTML][HTML] The real world effect of omalizumab add on therapy for patients with moderate to severe allergic asthma: The ASTERIX Observational study

M Bhutani, WH Yang, J Hébert, F de Takacsy, JL Stril - PLoS One, 2017 - journals.plos.org
Background Omalizumab is a non-steroidal medication indicated for the treatment of poorly
controlled moderate-to-severe allergic asthmatics. This observational study examines the …

[HTML][HTML] Omalizumab in patients with allergic (IgE-mediated) asthma and IgE/bodyweight combinations above those in the initially approved dosing table

O Kornmann, H Watz, R Fuhr, N Krug… - Pulmonary …, 2014 - Elsevier
Background When first approved in the European Union (EU), the omalizumab dosing table
had upper bodyweight and IgE limits of 150 kg and 700 IU/mL, respectively. In this study, we …

[HTML][HTML] Italian real-life experience of omalizumab

M Cazzola, G Camiciottoli, M Bonavia, C Gulotta… - Respiratory …, 2010 - Elsevier
Omalizumab is a humanized murine monoclonal antibody directed toward a portion of the
IgE indicated in Europe for the treatment of severe persistent allergic asthma, inadequately …