[HTML][HTML] The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

Autophagy and tumor suppression: recent advances in understanding the link between autophagic cell death pathways and tumor development

R Khosravi-Far, E White, S Bialik, A Kimchi - Programmed Cell Death in …, 2008 - Springer
Autophagy is a process by which the cell recycles its components through self-consumption
of cellular organelles and bulk cytoplasm. In times of stress, it serves to generate much …

Autophagy: an emerging target for cancer therapy

M Høyer-Hansen, M Jäättelä - Autophagy, 2008 - Taylor & Francis
Macroautophagy (hereafter referred to as autophagy) is a lysosomal catabolic pathway
whereby cells recycle macromolecules and organelles. The capacity of autophagy to …

Here, There Be Dragons: Charting Autophagy-Related Alterations in Human Tumors

CB Lebovitz, SB Bortnik, SM Gorski - Clinical Cancer Research, 2012 - AACR
Macroautophagy (or autophagy) is a catabolic cellular process that is both homeostatic and
stress adaptive. Normal cells rely on basal levels of autophagy to maintain cellular integrity …

[HTML][HTML] Role and regulation of autophagy in cancer

R Rakesh, LC PriyaDharshini, KM Sakthivel… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

[HTML][HTML] The spectrum of cell death in sarcoma

E Belyaeva, N Loginova, BA Schroeder… - Biomedicine & …, 2023 - Elsevier
The balance between cell death and cell survival is a highly coordinated process by which
cells break down and remove unnecessary or harmful materials in a controlled, highly …

Autophagy in cancer cell transformation: A potential novel therapeutic strategy

BA Marzoog - Current Cancer Drug Targets, 2022 - ingentaconnect.com
Basal autophagy plays a crucial role in maintaining intracellular homeostasis and prevents
the cell from escaping the cell cycle regulation mechanisms and being cancerous …

Autophagy: an adaptable modifier of tumourigenesis

S Wilkinson, KM Ryan - Current opinion in genetics & development, 2010 - Elsevier
Recently, autophagy has been demonstrated to modulate tumourigenesis and the response
to cancer therapy by regulating numerous cellular functions including maintenance of cell …

Apoptosis and autophagy: Targeting autophagy signalling in cancer cells–'trick or treats'?

EA Corcelle, P Puustinen, M Jäättelä - The FEBS journal, 2009 - Wiley Online Library
Macroautophagy (hereafter referred to as autophagy) is a tightly regulated lysosome‐
dependent catabolic pathway. During this process, cytosolic constituents are sequestered …

Autophagy as a critical driver of metabolic adaptation, therapeutic resistance, and immune evasion of cancer

K Yamamoto, D Iwadate, E Naito, K Tateishi… - Current Opinion in …, 2023 - Elsevier
Highlights•Autophagy is a catabolic pathway that mediates the degradation of intracellular
components.•Autophagy is highly activated in certain types of cancers.•Autophagy in host …