Different antiviral effects of IFNα and IFNβ in an HBV mouse model
Y Zhou, S Li, Z Tang, C Xu, S Huang, J Wu, U Dittmer… - Immunobiology, 2017 - Elsevier
Interferons α and β (IFNα and IFNβ) are type I interferons produced by the host to control
pathogen propagation. However, only a minority of chronic hepatitis B (CHB) patients …
pathogen propagation. However, only a minority of chronic hepatitis B (CHB) patients …
Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
J Song, S Li, Y Zhou, J Liu, S Francois, M Lu, D Yang… - Scientific Reports, 2017 - nature.com
Interferon alpha (IFNα) is commonly used for the treatment of chronic hepatitis B (CHB)
patients. There are 13 different IFNα subtypes in humans, but only the subtype IFNα2 is used …
patients. There are 13 different IFNα subtypes in humans, but only the subtype IFNα2 is used …
Effects of interferon-α/β on HBV replication determined by viral load
Interferons α and β (IFN-α/β) are type I interferons produced by the host to control microbial
infections. However, the use of IFN-α to treat hepatitis B virus (HBV) patients generated …
infections. However, the use of IFN-α to treat hepatitis B virus (HBV) patients generated …
Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice
M Lütgehetmann, T Bornscheuer, T Volz, L Allweiss… - Gastroenterology, 2011 - Elsevier
Background & Aims Interferon (IFN)-α therapy is not effective for most patients with chronic
hepatitis B virus (HBV) infection for reasons that are not clear. We investigated whether HBV …
hepatitis B virus (HBV) infection for reasons that are not clear. We investigated whether HBV …
The anti-HBV effect mediated by a novel recombinant eukaryotic expression vector for IFN-α
H Yu, Z Hou, Q Han, C Zhang, J Zhang - Virology journal, 2013 - Springer
Background Chronic hepatitis B is a primary cause of liver-related death. Interferon alpha
(IFN-α) is able to inhibit the replication of hepadnavirus, and the sustained and stable …
(IFN-α) is able to inhibit the replication of hepadnavirus, and the sustained and stable …
IFNα subtype-specific susceptibility of HBV in the course of chronic infection
X Xie, Z Karakoese, D Ablikim, J Ickler… - Frontiers in …, 2022 - frontiersin.org
Chronic hepatitis B virus (HBV) infection continues to be a major health problem worldwide
and remains hard to be cured. Therapy with interferon (IFN) α is an important method for the …
and remains hard to be cured. Therapy with interferon (IFN) α is an important method for the …
Role of ISGF3 in modulating the anti‐hepatitis B virus activity of interferon‐alpha in vitro
Q Zhang, Y Wang, L Wei, D Jiang… - Journal of …, 2008 - Wiley Online Library
Abstract Background and Aim: Although interferon‐α (IFN‐α) is an effective treatment for
hepatitis B virus (HBV) infection, its precise mechanism of action has not been identified. In …
hepatitis B virus (HBV) infection, its precise mechanism of action has not been identified. In …
Early application of IFNγ mediated the persistence of HBV in an HBV mouse model
J Song, X Sun, Y Zhou, S Li, J Wu, L Yang, D Zhou… - Antiviral Research, 2024 - Elsevier
The antiviral activity of interferon gamma (IFNγ) against hepatitis B virus (HBV) was
demonstrated both in vivo and in vitro in a previous study. IFNγ can suppress HBV …
demonstrated both in vivo and in vitro in a previous study. IFNγ can suppress HBV …
Type I interferons inhibit hepatitis B virus replication and induce hepatocellular gene expression in cultured liver cells
WH Caselmann, M Meyer, S Scholz… - Journal of Infectious …, 1992 - academic.oup.com
A hepatoblastoma cell line transfected with hepatitis B virus (HBV) DNA (Hep G2. 2.15) was
used to investigate the effects of interferons (IFNs) on HBV replication and hepatocellular …
used to investigate the effects of interferons (IFNs) on HBV replication and hepatocellular …
Anti‐viral effects of interferon‐λ3 on hepatitis B virus infection in cell culture
N Yamada, A Murayama, M Shiina, HH Aly… - Hepatology …, 2020 - Wiley Online Library
Aim Interferon (IFN)‐λ3 is known to have antiviral effects against various pathogens.
Recently, it has been reported that the production of IFN‐λ3 in colon cells after the …
Recently, it has been reported that the production of IFN‐λ3 in colon cells after the …