MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases

X Wang, Y He, B Mackowiak, B Gao - Gut, 2021 - gut.bmj.com
MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

[HTML][HTML] MicroRNA signatures in liver diseases

XM Chen - World journal of gastroenterology: WJG, 2009 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are an emerging class of highly conserved non-coding small RNAs
that regulate gene expression at the post-transcriptional level. It is now clear that miRNAs …

MicroRNAs in liver disease

G Szabo, S Bala - Nature reviews Gastroenterology & hepatology, 2013 - nature.com
Small, noncoding microRNAs (miRNAs) regulate diverse biological functions in the liver and
increasing evidence suggests that they have a role in liver pathology. This Review …

The role of miRNAs in liver diseases: Potential therapeutic and clinical applications

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

[HTML][HTML] microRNAs: fad or future of liver disease

AM Lakner, HL Bonkovsky… - World journal of …, 2011 - ncbi.nlm.nih.gov
Abstract microRNAs (miRs) are small non-coding RNAs that regulate both mRNA and
protein expression of target genes, which results in alterations in mRNA stability or …

[HTML][HTML] The role of miRNAs in the pathophysiology of liver diseases and toxicity

F Schueller, S Roy, M Vucur, C Trautwein… - International journal of …, 2018 - mdpi.com
Both acute and chronic liver toxicity represents a major global health burden and an
important cause of morbidity and lethality worldwide. Despite epochal progress in the …

[HTML][HTML] MicroRNAs and liver disease

M Otsuka, T Kishikawa, T Yoshikawa… - Journal of human …, 2017 - nature.com
The biological roles of microRNAs (miRNAs) have been extensively studied. miRNA122
represents more than half of the miRNAs expressed in the liver and has various …

[HTML][HTML] miR-122, a paradigm for the role of microRNAs in the liver

M Girard, E Jacquemin, A Munnich, S Lyonnet… - Journal of …, 2008 - Elsevier
Recent studies have uncovered profound and unexpected roles for a family of tiny regulatory
RNAs, known as microRNAs (miRNAs), in the control of diverse aspects of hepatic function …

Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation

D Blaya, M Coll, D Rodrigo-Torres, M Vila-Casadesús… - Gut, 2016 - gut.bmj.com
Objective MicroRNAs (miRNAs) are well-known regulators of disease pathogenesis and
have great potential as biomarkers and therapeutic targets. We aimed at profiling miRNAs in …

MicroRNAs in liver disease

XW Wang, NHH Heegaard, H Ørum - Gastroenterology, 2012 - Elsevier
MicroRNAs are small noncoding RNA molecules that regulate gene expression
posttranscriptionally through complementary base pairing with thousands of messenger …