[HTML][HTML] Identification of broad-spectrum neutralizing antibodies against influenza A virus and evaluation of their prophylactic efficacy in mice
S Son, SB Ahn, G Kim, Y Jang, C Ko, M Kim, SJ Kim - Antiviral Research, 2023 - Elsevier
Influenza A virus continuously infects humans and the antigenic shifts of this respiratory virus
enable it to cross the species barrier, threatening public health with the risk of pandemics …
enable it to cross the species barrier, threatening public health with the risk of pandemics …
Human single-chain antibodies that neutralize homologous and heterologous strains and clades of influenza A virus subtype H5N1
S Maneewatch, J Thanongsaksrikul… - Antiviral …, 2009 - journals.sagepub.com
Background Human antibodies that interfere with the biological activity of haemagglutinins
(HAs) of influenza viruses have high potential as an antiviral agent. Methods Human single …
(HAs) of influenza viruses have high potential as an antiviral agent. Methods Human single …
Generation and characterization of monoclonal antibodies against the hemagglutinin of H3N2 influenza A viruses
F Yang, L Zhu, F Liu, L Cheng, H Yao, N Wu, H Wu, L Li - Virus Research, 2022 - Elsevier
Seasonal influenza viruses are highly contagious, leading to 290,000–650,000 mortalities
every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted …
every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted …
Broadly neutralizing antibodies recognizing different antigenic epitopes act synergistically against the influenza B virus
L Zhai, L Zhang, Y Jiang, B Li, M Yang… - Journal of Medical …, 2023 - Wiley Online Library
The discovery of broadly neutralizing monoclonal antibodies against influenza viruses has
raised hope for the successful development of new antiviral drugs. However, due to the …
raised hope for the successful development of new antiviral drugs. However, due to the …
Human monoclonal antibodies neutralizing influenza virus A/H1N1pdm09 and seasonal A/H1N1 strains–Distinct Ig gene repertoires with a similar action mechanism
S Hiroi, M Kuhara, Y Kishi, K Ono, S Matsuzawa… - Immunobiology, 2018 - Elsevier
Influenza virus causes acute respiratory infection in humans, and is a major public health
concern globally. Antibodies play a central role in host protection against influenza virus. We …
concern globally. Antibodies play a central role in host protection against influenza virus. We …
An universal approach to getting ahead for influenza B vaccines
Cross-reactive neutralizing antibodies against influenza A viruses have received attention
for their potentials for prophylactic and therapeutic. These antibodies usually bind to …
for their potentials for prophylactic and therapeutic. These antibodies usually bind to …
Human monoclonal antibody derived from transchromosomic cattle neutralizes multiple H1 clades of influenza A virus by recognizing a novel conformational epitope …
Influenza remains a global health risk and challenge. Currently, neuraminidase (NA)
inhibitors are extensively used to treat influenza, but their efficacy is compromised by the …
inhibitors are extensively used to treat influenza, but their efficacy is compromised by the …
Human monoclonal antibody 81.39 a effectively neutralizes emerging influenza A viruses of group 1 and 2 hemagglutinins
H Marjuki, VP Mishin, N Chai, MW Tan… - Journal of …, 2016 - Am Soc Microbiol
The pandemic threat posed by emerging zoonotic influenza A viruses necessitates
development of antiviral agents effective against various antigenic subtypes. Human …
development of antiviral agents effective against various antigenic subtypes. Human …
A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo
Seasonal epidemics caused by antigenic variations in influenza A virus remain a public
health concern and an economic burden. The isolation and characterization of broadly …
health concern and an economic burden. The isolation and characterization of broadly …
Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin
Due to continuous changes to its antigenic regions, influenza viruses can evade immune
detection and cause a significant amount of morbidity and mortality around the world …
detection and cause a significant amount of morbidity and mortality around the world …