Increase of CD8+ T-effector memory cells in peripheral blood of patients with relapsing–remitting multiple sclerosis compared to healthy controls

KF Haegele, CA Stueckle, JP Malin… - Journal of …, 2007 - Elsevier
CCR7 and CD45RA expression on CD4+ and CD8+ T-cells in blood (PB) of 16 patients with
multiple sclerosis (MS) and 16 healthy controls and cerebrospinal fluid (CSF) of 10 patients …

The activation of memory CD4+ T cells and CD8+ T cells in patients with multiple sclerosis

Y Okuda, M Okuda, BR Apatoff, DN Posnett - Journal of the neurological …, 2005 - Elsevier
To reevaluate whether an association exists between the clinical course of multiple sclerosis
(MS) and the activation of memory T cells, we investigated the phenotype of T cells in …

Increased CD8+ central memory T cells in patients with multiple sclerosis

GZ Liu, LB Fang, P Hjelmström… - Multiple Sclerosis …, 2007 - journals.sagepub.com
AT-cell-mediated autoimmune process against central nervous system myelin is believed to
underlie the pathogenesis of multiple sclerosis (MS). Formation of immunological memory is …

Reduced Frequency of Memory CD8+ T Lymphocytes in Cerebrospinal Fluid and Blood of Patients with Multiple Sclerosis

A Svenningsson, O Andersen, GK Hansson… - Autoimmunity, 1995 - Taylor & Francis
Three color flow cytometry was used to analyze immunoregulatory lymphocyte subsets in
peripheral blood (PB) and cerebrospinal fluid (CSF) of 21 patients with multiple sclerosis …

Characterization of naïve, memory and effector T cells in progressive multiple sclerosis

BR Nielsen, R Ratzer, L Börnsen, MR von Essen… - Journal of …, 2017 - Elsevier
We characterized naïve, central memory (CM), effector memory (EM) and terminally
differentiated effector memory (TEMRA) CD4+ and CD8+ T cells and their expression of …

[HTML][HTML] Characterization of antigen-specific CD8+ memory T cell subsets in peripheral blood of patients with multiple sclerosis

PJ Liu, TT Yang, ZX Fan, GB Yuan, L Ma… - Frontiers in …, 2023 - frontiersin.org
Background Increasing evidence indicates the importance of CD8+ T cells in autoimmune
attack against CNS myelin and axon in multiple sclerosis (MS). Previous research has also …

Memory and naive CD4+ lymphocytes in multiple sclerosis

AM Porrini, D Gambi, G Malatesta - Journal of neurology, 1992 - Springer
Summary Helper-inducer (CD29+ CD4+) and suppressor (CD45RACD4+) T-cells have
been recently renamed as memory and naive T-cells, respectively. We measured cells …

Phenotypic characterization of autoreactive T cells in multiple sclerosis

RB Ratts, NJ Karandikar, RZ Hussain, J Choy… - Journal of …, 2006 - Elsevier
MS has been hypothesized to result from autoreactive T cell responses against myelin
antigens. In this report, we examined myelin-specific CD8 and CD4 T cells for two markers …

Decrease of CD4+ CD45+ T-cells in chronic-progressive multiple sclerosis

M Zaffaroni, S Rossini, A Ghezzi, R Parma… - Journal of …, 1990 - Springer
Circulating lymphocyte subpopulations defined by anti-CD45 and other more common T-cell-
specific monoclonal antibodies were analysed in 77 patients with multiple sclerosis and 38 …

CD4 and CD8 lymphocyte subsets in cerebrospinal fluid and peripheral blood from patients with multiple sclerosis, meningitis and normal controls

M Vrethem, C Dahle, C Ekerfelt… - Acta neurologica …, 1998 - Wiley Online Library
Objectives‐To study the distribution of CD4+ and CD8+ T‐cell subsets in cerebrospinal fluid
(CSF) and peripheral blood from patients with multiple sclerosis (MS), meningitis, other …