Studies of serotonin metabolites in body fluids in attempted suicide patients and of post-
mortem brain tissue of suicide victims have demonstrated the involvement of the …

Among the recently cloned serotonin (5-hydroxytryptamine, 5-HT) receptors, the 5-HT6
subtype is of special interest for at least two reasons: 1) it is abundant in limbic areas which …

Neural function within the medial prefrontal cortex (mPFC) regulates normal cognition,
attention and impulse control, implicating neuroregulatory abnormalities within this region in …

The regional distribution of the mRNA encoding the 5-HT 1A serotonin receptor (whose
selective agonists are potential anxiolytic and antidepressant drugs) was investigated in rat …

HT 2 receptor binding sites were measured (by saturation binding of [3 H] ketanserin) in
brain tissue obtained at postmortem from 19 suicide victims with definite evidence of …

We have examined the distribution of 5-HT1A and 5-HT2A receptor mRNAs in post-mortem
human hippocampus, neocortex, raphe nuclei, cerebellum and basal ganglia using in situ …

Background Postmortem and brain imaging studies that measured brain serotinin 2 (5-HT 2)
receptors in major depression reported an increase, decrease, and no change compared …

Specific binding for the 5-HT 4-selective radioligand [3 H] GR 113808 has been identified in
human and calf brain membranes. Using human tissue the distribution of the binding was …

The 5-HT uptake sites were studied with [3H] paroxetine as radioligand in frontal cortex,
cingulate cortex and hypothalamus from a control group (n= 22) and a group of suicide …

p11 is an adaptor protein which binds to serotonin 5-HT1B receptors and 5-HT4 receptors
and regulates their localization at the cell surface. In the present study, we examined to what …