Apolipoprotein (a) gene accounts for greater than 90% of the variation in plasma lipoprotein (a) concentrations.
E Boerwinkle, CC Leffert, J Lin… - The Journal of …, 1992 - Am Soc Clin Investig
Plasma lipoprotein (a)[Lp (a)], a low density lipoprotein particle with an attached
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …
Sequence polymorphisms in the apo (a) gene associated with specific levels of Lp (a) in plasma
V Mooser, FP Mancini, S Bopp… - Human molecular …, 1995 - academic.oup.com
Most of the Interindividual variations in plasma levels of lipoprotein (a)[Lp (a)] can be
attributed to sequence differences linked to the apolipoprotein (a)[apo (a)] locus. Plasma …
attributed to sequence differences linked to the apolipoprotein (a)[apo (a)] locus. Plasma …
Sequence polymorphisms in the apolipoprotein (a) gene. Evidence for dissociation between apolipoprotein (a) size and plasma lipoprotein (a) levels.
JC Cohen, G Chiesa, HH Hobbs - The Journal of clinical …, 1993 - Am Soc Clin Investig
Apolipoprotein (a)[apo (a)], an apolipoprotein unique to lipoprotein (a)[Lp (a)], is highly
polymorphic in size. Previous studies have indicated that the size of the apo (a) gene tends …
polymorphic in size. Previous studies have indicated that the size of the apo (a) gene tends …
Variation in lipoprotein (a) concentration associated with different apolipoprotein (a) alleles.
YF Perombelon, AK Soutar… - The Journal of clinical …, 1994 - Am Soc Clin Investig
Plasma lipoprotein (a)(Lp (a)) concentrations vary considerably between individuals. To
examine the variation for products of the same and different apolipoprotein (a)(apo (a)) …
examine the variation for products of the same and different apolipoprotein (a)(apo (a)) …
The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration
HG Kraft, S Köchl, HJ Menzel, C Sandholzer… - Human genetics, 1992 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a quantitative trait in human plasma. Lp (a) consists of a
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …
A pentanucleotide repeat polymorphism in the 5'control region of the apolipoprotein (a) gene is associated with lipoprotein (a) plasma concentrations in Caucasians.
M Trommsdorff, S Köchl, A Lingenhel… - The Journal of …, 1995 - Am Soc Clin Investig
The enormous interindividual variation in the plasma concentrations of the atherogenic
lipoprotein (a)[Lp (a)] is almost entirely controlled by the apo (a) locus on chromosome 6q26 …
lipoprotein (a)[Lp (a)] is almost entirely controlled by the apo (a) locus on chromosome 6q26 …
Genetics of the quantitative Lp (a) lipoprotein trait: III. Contribution of Lp (a) glycoprotein phenotypes to normal lipid variation
E Boerwinkle, HJ Menzel, HG Kraft, G Utermann - Human genetics, 1989 - Springer
Summary Apolipoprotein (a)[apo (a)] is a large serum glycoprotein with several genetically
determined isoforms differing in their apparent molecular weight. We determined the effects …
determined isoforms differing in their apparent molecular weight. We determined the effects …
Comparative analysis of the apo (a) gene, apo (a) glycoprotein, and plasma concentrations of Lp (a) in three ethnic groups. Evidence for no common" null" allele at the …
A Gaw, E Boerwinkle, JC Cohen… - Journal of Clinical …, 1994 - ncbi.nlm.nih.gov
Distributions of plasma lipoprotein (a)(Lp [a]) concentrations exhibit marked interracial
differences. Apolipoprotein (a)(apo [a]), the unique constituent of Lp (a), is highly …
differences. Apolipoprotein (a)(apo [a]), the unique constituent of Lp (a), is highly …
Expressed hypervariable polymorphism of apolipoprotein (a).
MI Kamboh, RE Ferrell, BA Kottke - American journal of human …, 1991 - ncbi.nlm.nih.gov
Elevated plasma lipoprotein (a)(LP (a] levels are an independent predictor of the
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
Molecular definition of the extreme size polymorphism in apolipoprotein (a)
C Lackner, JC Cohen, HH Hobbs - Human molecular genetics, 1993 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)], an atherogenic lipoprotein, consists of an LDL particle
complexed with a large glycoprotein, apollpoprotein (a)[apo (a)]. Apo (a) is one of the most …
complexed with a large glycoprotein, apollpoprotein (a)[apo (a)]. Apo (a) is one of the most …