Engineering synthetic vaccines using cues from natural immunity
Vaccines aim to protect against or treat diseases through manipulation of the immune
response, promoting either immunity or tolerance. In the former case, vaccines generate …
response, promoting either immunity or tolerance. In the former case, vaccines generate …
Materials engineering for immunomodulation
The engineering of materials that can modulate the immune system is an emerging field that
is developing alongside immunology. For therapeutic ends such as vaccine development …
is developing alongside immunology. For therapeutic ends such as vaccine development …
Designing natural and synthetic immune tissues
EA Gosselin, HB Eppler, JS Bromberg, CM Jewell - Nature materials, 2018 - nature.com
Vaccines and immunotherapies have provided enormous improvements for public health,
but there are fundamental disconnects between where most studies are performed—in cell …
but there are fundamental disconnects between where most studies are performed—in cell …
Biomaterials as tools to decode immunity
HB Eppler, CM Jewell - Advanced Materials, 2020 - Wiley Online Library
The immune system has remarkable capabilities to combat disease with exquisite selectivity.
This feature has enabled vaccines that provide protection for decades and, more recently …
This feature has enabled vaccines that provide protection for decades and, more recently …
Biomaterials-mediated engineering of the immune system
C Backlund, S Jalili-Firoozinezhad… - Annual review of …, 2023 - annualreviews.org
Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
Improving vaccine and immunotherapy design using biomaterials
ML Bookstaver, SJ Tsai, JS Bromberg, CM Jewell - Trends in immunology, 2018 - cell.com
Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …
technologies to improve the efficacy of vaccines against infectious disease and …
Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Biomaterial strategies for immunomodulation
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …
importance for diverse biomedical applications, such as the development of new vaccines …
Harnessing innate immunity using biomaterials for cancer immunotherapy
The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …
oncology and established the foundation for developing various new therapies that can …
Immunologically effective biomaterials
Q Wei, Y Su, H Xin, L Zhang, J Ding… - ACS Applied Materials & …, 2021 - ACS Publications
Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …
and chemical properties of biomaterials offer tremendous opportunities for development …