Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity

GL Schwartz, ST Turner - Clinical chemistry, 2005 - academic.oup.com
Background: The ratio of plasma aldosterone concentration to plasma renin activity (PRA) is
considered the screening test of choice for primary aldosteronism. Uncertainty exists …

Validity of the aldosterone-renin ratio used to screen for primary aldosteronism

VM Montori, GL Schwartz, AB Chapman… - Mayo Clinic …, 2001 - Elsevier
Objective To determine whether the calculated ratio of plasma aldosterone concentration
(PAC) to plasma renin activity (PRA), a proposed screening test for primary aldosteronism …

Use of plasma aldosterone concentration-to-plasma renin activity ratio as a screening test for primary aldosteronism: a systematic review of the literature

VM Montori, WF Young - Endocrinology and Metabolism Clinics, 2002 - endo.theclinics.com
Objective. We conducted a systematic review of the literature to establish the test
characteristics (sensitivity, specificity, likelihood ratios at different cutoff values) of the …

Test characteristics of the aldosterone-to-renin ratio as a screening test for primary aldosteronism

PM Jansen, BJH van den Born, WJ Frenkel… - Journal of …, 2014 - journals.lww.com
Background: The aldosterone-to-renin ratio (ARR) is a widely used screening test for
primary aldosteronism. Current guidelines recommend a cut-off value of 91 pmol/mU …

Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio

GL Schwartz, AB Chapman, E Boerwinkle… - Clinical …, 2002 - academic.oup.com
Background: The value of the ratio of plasma aldosterone concentration (aldosterone) to
plasma renin activity (renin) to identify patients at risk for primary aldosteronism is …

Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism: need for a standardized protocol

G Giacchetti, V Ronconi, G Lucarelli… - Journal of …, 2006 - journals.lww.com
Background The upright serum aldosterone/upright plasma renin activity ratio (ARR) has
been recommended as a screening tool for the diagnosis of primary aldosteronism …

The use of aldosterone-renin ratio as a diagnostic test for primary hyperaldosteronism and its test characteristics under different conditions of blood sampling

SC Tiu, CH Choi, CC Shek, YW Ng… - The Journal of …, 2005 - academic.oup.com
Recent reviews recommended the use of the aldosterone/renin ratio (ARR) to screen for
primary hyperaldosteronism. However, widely different cutoff levels have been proposed …

Within-patient reproducibility of the aldosterone: renin ratio in primary aldosteronism

GP Rossi, TM Seccia, G Palumbo, A Belfiore… - …, 2010 - Am Heart Assoc
The plasma aldosterone concentration: renin ratio (ARR) is widely used for the screening of
primary aldosteronism, but its reproducibility is unknown. We, therefore, investigated the …

Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio

BJ Gallay, S Ahmad, L Xu, B Toivola… - American Journal of …, 2001 - Elsevier
The traditional workup for primary aldosteronism is cumbersome and requires discontinuing
antihypertensive medications, which is inconvenient and potentially dangerous. A simple …

[PDF][PDF] The aldosterone-to-renin ratio as a screening test for primary aldosteronism.

PM Jansen, F Boomsma, AH van den Meiracker - THE ROLE OF, 2008 - repub.eur.nl
Since the introduction of the aldosterone-to-renin ratio (ARR) as a screening test for primary
aldosteronism (PA), there has been a marked increase in the reported prevalence of this …