DNA repair is central to normal cellular functions, and polymorphisms of DNA repair genes
may cause variation in DNA repair capacity in the general population. Newly identified …

Variation in DNA repair capacity, which is believed to be largely determined by genetic traits,
is linked to risk of certain cancers. The Asp312Asn and Lys751Gln polymorphisms in the …

Interindividual variation in lung cancer susceptibility may be modulated in part through
genetic polymorphisms in the DNA repair genes, especially the genes involved in the …

Background The nucleotide excision repair (NER) protein, xeroderma pigmentosum C
(XPC), participates in recognizing DNA lesions and initiating DNA repair in response to DNA …

Previous studies suggested that suboptimal DNA repair capacity is associated with cancer
risk and that the Asp312Asn and Lys751Gln polymorphisms in the xeroderma pigmentosum …

Abstract Polymorphisms (A33512C, C21151T and PAT−/+) of the xeroderma pigmentosum
group C (XPC) were shown to contribute to genetic susceptibility to cancer. However …

To determine the effect of the DNA repair gene XPD Arg156Arg polymorphism on the risk of
lung cancer in a North-Eastern Chinese population, a hospital-based case-control study was …

Polymorphisms in DNA repair genes may be associated with differences in the capacity to
repair DNA damage and thereby influence an individual's susceptibility to smoking‐related …

DNA repair plays a critical role in protecting the genome from insults of cancer-causing
agents, such as those found in tobacco smoke. Therefore, reduced DNA repair capacity can …

X-ray repair cross-complementing group 1 (XRCC1) and xeroderma pigmentosum group D
(XPD) are mainly involved in base excision repair (BER) and nucleotide excision repair …