Interferon‐β1a therapy in human T‐lymphotropic virus type I–associated neurologic disease

U Oh, Y Yamano, CA Mora, J Ohayon… - Annals of …, 2005 - Wiley Online Library
Human T‐lymphotropic virus type I (HTLV‐I)–associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is an immune‐mediated inflammatory disorder of the central …

Long term, high dose interferon-alpha treatment in HTLV-I-associated myelopathy/tropical spastic paraparesis: a combined clinical, virological and immunological …

K Yamasaki, J Kira, Y Koyanagi, Y Kawano… - Journal of the …, 1997 - Elsevier
The efficacy of long-term, high dose interferon-α (IFN-α) therapy was studied in seven
patients with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP). IFN-α …

HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP): a chronic progressive neurologic disease associated with immunologically mediated damage …

MC Levin, S Jacobson - Journal of neurovirology, 1997 - Taylor & Francis
This review examines information on clinical, pathological and immunological events in the
slowly progressive neurologic disorder associated with the human T lymphotropic virus type …

HTLV-I specific IFN-γ+ CD8+ lymphocytes correlate with the proviral load in peripheral blood of infected individuals

R Kubota, T Kawanishi, H Matsubara, A Manns… - Journal of …, 2000 - Elsevier
Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is an inflammatory neurological disease caused by HTLV-I infection …

Accumulation of human T-lymphotropic virus type I (HTLV-I)-infected cells in the cerebrospinal fluid during the exacerbation of HTLV-I-associated myelopathy

D Hayashi, R Kubota, N Takenouchi, T Nakamura… - Journal of …, 2008 - Springer
Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a slowly progressive, inflammatory disease of the central nervous …

Immunopathogenesis of human T cell lymphotropic virus type I–associated neurologic disease

S Jacobson - The Journal of infectious diseases, 2002 - academic.oup.com
This review focuses on current approaches to understanding the immunopathogenesis of
human T cell lymphotropic virus (HTLV) type I–associated myelopathy/tropical spastic …

Reduction in HTLV‐I proviral load and spontaneous lymphoproliferation in HTLV‐I–associated myelopathy/tropical spastic paraparesis patients treated with …

TJ Lehky, MC Levin, R Kubota… - Annals of Neurology …, 1998 - Wiley Online Library
Human T‐lymphotropic virus type I (HTLV‐I)‐associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a neurological disease that results from an interaction of retroviral …

Virological aspects of tropical spastic paraparesis/HTLV-I associated myelopathy and HTLV-I infection

A Gessain - Journal of neurovirology, 1996 - Taylor & Francis
TSP/HAM, a chronic spastic paraparesis or paraplegia with sphincter disturbances and
minimal sensory loss, is characterized pathologically by a meningo-myelitis of the lower …

Human T-cell lymphotropic virus type I and neurological diseases

M Nagai, M Osame - Journal of neurovirology, 2003 - Springer
Human T-cell lymphotropic virus type I (HTLV-I) infection is associated with a variety of
human diseases. In particular, there are two major diseases caused by HTLV-I infection …

Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis

K Barmak, EW Harhaj, B Wigdahl - Journal of neurovirology, 2003 - Springer
Human T-cell leukemia virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) represents one of the most devastating diseases associated with …