Anfibatide alleviates inflammation and apoptosis via inhibiting NF-kappaB/NLRP3 axis in ischemic stroke
R Li, M Si, HY Jia, Z Ma, XW Li, XY Li, XR Dai… - European Journal of …, 2022 - Elsevier
Recent evidence suggests that Nod-like receptor protein-3 (NLRP3) inflammasome is a key
mediator of inflammatory response and can induce the activation of apoptosis signaling …
mediator of inflammatory response and can induce the activation of apoptosis signaling …
MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson's disease
Y Zhou, M Lu, RH Du, C Qiao, CY Jiang… - Molecular …, 2016 - Springer
Abstract Background α-Synuclein (α-Syn), a pathological hallmark of Parkinson's disease
(PD), has been recognized to induce the production of interleukin-1β in a process that …
(PD), has been recognized to induce the production of interleukin-1β in a process that …
Glucocorticoid-driven NLRP3 inflammasome activation in hippocampal microglia mediates chronic stress-induced depressive-like behaviors
X Feng, Y Zhao, T Yang, M Song, C Wang… - Frontiers in molecular …, 2019 - frontiersin.org
Chronic stress is a key risk factor for depression, and microglia have been implicated in the
pathogenesis of the disease. Recent studies show that the Nod-like receptor protein 3 …
pathogenesis of the disease. Recent studies show that the Nod-like receptor protein 3 …
Fluoxetine-enhanced autophagy ameliorates early brain injury via inhibition of NLRP3 inflammasome activation following subarachnoid hemorrhage in rats
J Li, H Xu, S Nie, Y Peng, LF Fan, Z Wang… - Journal of …, 2017 - Springer
Background The NLRP3 inflammasome is a multiprotein complex that regulates the innate
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …
immune inflammatory response by activating caspase-1 and subsequent IL-1β and IL-18 …
Hyperbaric oxygen alleviates the activation of NLRP‑3‑inflammasomes in traumatic brain injury
H Qian, Q Li, W Shi - Molecular medicine reports, 2017 - spandidos-publications.com
Growing evidence has demonstrated that the nucleotide‑binding oligomerization domain‑
like receptor family pyrin domain containing 3 (NLRP‑3) inflammasome‑mediated …
like receptor family pyrin domain containing 3 (NLRP‑3) inflammasome‑mediated …
NLRP3 inflammasome mediates neurodegeneration in rats with chronic neuropathic pain
C Ren, M Chen, G Mu, S Peng, X Liu, C Ou - Shock, 2021 - journals.lww.com
Patients with chronic neuropathic pain (NP) have a significantly increased risk of central
nervous degeneration. Trigeminal neuralgia (TN) is a typical NP, and this manifestation is …
nervous degeneration. Trigeminal neuralgia (TN) is a typical NP, and this manifestation is …
Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury
Y Hou, Y Wang, Q He, L Li, H Xie, Y Zhao… - Behavioural brain …, 2018 - Elsevier
The nod-like receptor protein 3 (NLRP3) inflammasome has a critical role in inflammation
damage in ischemic injury, and the activation of the inflammasome is closely related to the …
damage in ischemic injury, and the activation of the inflammasome is closely related to the …
NLRP3 inflammasome activation increases brain oxidative stress after transient global cerebral ischemia in rats
LS Joaquim, LG Danielski, S Bonfante… - International Journal …, 2023 - Taylor & Francis
Pupurpose of the study: Oxidative stress has been reported to be an important mechanism
for brain damage following ischemic stroke. Recently, the involvement of cytosolic receptors …
for brain damage following ischemic stroke. Recently, the involvement of cytosolic receptors …
Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia
A Palomino‐Antolin… - British journal of …, 2022 - Wiley Online Library
Background Inflammasomes are cytosolic multiprotein complexes which, upon assembly,
activate the maturation and secretion of the inflammatory cytokines IL‐1β and IL‐18 …
activate the maturation and secretion of the inflammatory cytokines IL‐1β and IL‐18 …
Meisoindigo protects against focal cerebral ischemia-reperfusion injury by inhibiting NLRP3 inflammasome activation and regulating microglia/macrophage …
Y Ye, T Jin, X Zhang, Z Zeng, B Ye, J Wang… - Frontiers in cellular …, 2019 - frontiersin.org
Ischemic stroke is a devastating disease with long-term disability. However, the
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …
pathogenesis is unclear and treatments are limited. Meisoindigo, a second-generation …