[HTML][HTML] Hybrid gold (I) NHC-artemether complexes to target falciparum malaria parasites
M Ouji, G Barnoin, Á Fernández Álvarez, JM Augereau… - Molecules, 2020 - mdpi.com
The emergence of Plasmodium falciparum parasites, responsible for malaria disease,
resistant to antiplasmodial drugs including the artemisinins, represents a major threat to …
resistant to antiplasmodial drugs including the artemisinins, represents a major threat to …
An overview of auric compounds as antimalarial agents and their action against essential targets of the parasite
GYS Delgado, M Navarro - Coordination Chemistry Reviews, 2024 - Elsevier
Malaria is one of the oldest and deadliest parasitic diseases globally, and it still poses a
global health issue today because of the emergence of new strains resistant to the first-line …
global health issue today because of the emergence of new strains resistant to the first-line …
Design, Synthesis and Efficacy of Hybrid Triclosan‐gold Based Molecules on Artemisinin‐resistant Plasmodium falciparum and Leishmania infantum Parasites
M Ouji, SB Delmas, ÁF Álvarez, JM Augereau… - …, 2020 - Wiley Online Library
The emergence of resistant parasites, Plasmodium and Leishmania, responsible of malaria
and leishmaniasis diseases, to the currently available drugs, remains one of the major …
and leishmaniasis diseases, to the currently available drugs, remains one of the major …
Antiplasmodial activities of gold (I) complexes involving functionalized N-heterocyclic carbenes
C Hemmert, AP Ramadani, L Boselli, AF Alvarez… - Bioorganic & medicinal …, 2016 - Elsevier
A series of twenty five molecules, including imidazolium salts functionalized by N-, O-or S-
containing groups and their corresponding cationic, neutral or anionic gold (I) complexes …
containing groups and their corresponding cationic, neutral or anionic gold (I) complexes …
A Novel hybrid of chloroquine and primaquine linked by Gold (I): Multitarget and multiphase antiplasmodial agent
C de Souza Pereira, H Costa Quadros… - …, 2021 - Wiley Online Library
Plasmodium parasites kill 435 000 people around the world every year due to unavailable
vaccines, a limited arsenal of antimalarial drugs, delayed treatment, and the reduced clinical …
vaccines, a limited arsenal of antimalarial drugs, delayed treatment, and the reduced clinical …
Synthesis, structures, and antimalarial activities of some silver (I), gold (I) and gold (III) complexes involving N-heterocyclic carbene ligands
C Hemmert, A Fabié, A Fabre, F Benoit-Vical… - European journal of …, 2013 - Elsevier
A series of mono-and dinuclear silver (I) and mononuclear gold (I) complexes containing bis
(N-heterocyclic carbene)(NHC) or N-functionalized NHC ligands were synthesized and fully …
(N-heterocyclic carbene)(NHC) or N-functionalized NHC ligands were synthesized and fully …
Synthesis, in vitro antiplasmodial activity and cytotoxicity of a series of artemisinin–triazine hybrids and hybrid-dimers
A series of artemisinin–triazine hybrids and hybrid-dimers were synthesized and their in vitro
antimalarial activity against the chloroquine sensitive (CQS), the gametocytocidal (NF54) …
antimalarial activity against the chloroquine sensitive (CQS), the gametocytocidal (NF54) …
Gold complexes as antimicrobial agents: an overview of different biological activities in relation to the oxidation state of the gold ion and the ligand structure
Interest in antimicrobial gold complexes originated from the work of Robert Koch at the end
of 19th century, who demonstrated that potassium dicyanidoaurate (I), K [Au (CN) 2], showed …
of 19th century, who demonstrated that potassium dicyanidoaurate (I), K [Au (CN) 2], showed …
Novel metalloantimalarials: Transmission blocking effects of water soluble Cu (I), Ag (I) and Au (I) phosphane complexes on the murine malaria parasite Plasmodium …
The water soluble phosphane complexes [M (L) 4] PF 6 (M= Cu (I), Ag (I)) and [Au (L) 4] Cl
(L= thp (tris (hydroxymethyl) phosphane) or PTA (1, 3, 5-triaza-7-phosphaadamantane)) …
(L= thp (tris (hydroxymethyl) phosphane) or PTA (1, 3, 5-triaza-7-phosphaadamantane)) …
Gold complexes as potential anti-parasitic agents
M Navarro - Coordination Chemistry Reviews, 2009 - Elsevier
The medical uses of gold have a long history; rheumatoid arthritis is currently treated with
gold-based drugs and there is increasing interest in the application of gold complexes as …
gold-based drugs and there is increasing interest in the application of gold complexes as …