Fixed-combination intraocular pressure-lowering therapy for glaucoma and ocular hypertension: advantages in clinical practice

G Holló, F Topouzis, RD Fechtner - Expert Opinion on …, 2014 - Taylor & Francis
Introduction: Several large, randomized, prospective clinical trials have demonstrated that
medical therapy to reduce intraocular pressure (IOP) delays the onset and decreases …

Considerations in glaucoma therapy: fixed combinations versus their component medications

EJ Higginbotham - Clinical Ophthalmology, 2010 - Taylor & Francis
Fixed combinations of medications that lower intraocular pressure (IOP) are increasingly
used in the treatment of glaucoma and ocular hypertension and offer several potential …

Effectiveness of intraocular pressure–lowering medication determined by washout

HD Jampel, BH Chon, R Stamper, M Packer… - JAMA …, 2014 - jamanetwork.com
Importance While medication efficacy is well documented in clinical trials, less is known of
medication effectiveness in real-world clinical settings. Objective To assess the effectiveness …

Achievements and limits of current medical therapy of glaucoma

P Kalouda, C Keskini, E Anastasopoulos… - Glaucoma surgery, 2017 - karger.com
Prescribing medical therapy for the treatment of glaucoma can be a complex process since
many parameters should be taken into consideration regarding its achievements and limits …

Intraocular pressure-lowering combination therapies with prostaglandin analogues

F Aptel, C Chiquet, JP Romanet - Drugs, 2012 - Springer
Intraocular pressure (IOP) reduction is currently the only therapeutic approach demonstrated
to preserve visual function in patients with glaucoma. The first line of glaucoma treatment …

Use of fixed-dose combination drugs for the treatment of glaucoma

AS Khouri, T Realini, RD Fechtner - Drugs & aging, 2007 - Springer
Glaucoma is a leading cause of irreversible visual loss. This potentially blinding disease is a
progressive optic neuropathy associated with elevated intraocular pressure (IOP). Initial …

Efficacy of antiglaucoma fixed combination therapy versus unfixed components in reducing intraocular pressure: a systematic review

JA Cox, SP Mollan, J Bankart… - British journal of …, 2008 - bjo.bmj.com
Aim: To evaluate the efficacy of the fixed combination ocular hypotensive therapies
compared with their non-fixed components used concomitantly for lowering intraocular …

The management of glaucoma and intraocular hypertension: current approaches and recent advances

RJ Noecker - Therapeutics and clinical risk management, 2006 - Taylor & Francis
In the last decade, numerous novel ocular hypotensive agents have been introduced for the
control of intraocular pressure (IOP). Clinicians now have more options than ever in the …

New pharmacotherapy for the treatment of glaucoma

EM Schehlein, G Novack, AL Robin - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Glaucoma is the second leading cause of blindness in the world and current
pharmacotherapies for glaucoma have remained relatively unchanged (with the exception of …

Intraocular pressure–lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials

R van der Valk, CAB Webers, JSAG Schouten… - Ophthalmology, 2005 - Elsevier
OBJECTIVE: To estimate the intraocular pressure (IOP) reduction achieved by the most
frequently prescribed glaucoma drugs and a placebo in a meta-analysis of randomized …