Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer's disease
Q Zeng, M Zheng, T Zhang, G He - Neuroscience, 2016 - Elsevier
Alzheimer's disease (AD) is one of the most common causes of dementia. Although the
exact mechanisms of AD are not entirely clear, the impairment in adult hippocampal …
exact mechanisms of AD are not entirely clear, the impairment in adult hippocampal …
[HTML][HTML] Early changes in hippocampal neurogenesis in transgenic mouse models for Alzheimer's disease
MS Unger, J Marschallinger, J Kaindl, C Höfling… - Molecular …, 2016 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the Western
world and is characterized by a progressive loss of cognitive functions leading to dementia …
world and is characterized by a progressive loss of cognitive functions leading to dementia …
[HTML][HTML] Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease
It has become generally accepted that new neurones are added and integrated mainly in
two areas of the mammalian CNS, the subventricular zone and the subgranular zone (SGZ) …
two areas of the mammalian CNS, the subventricular zone and the subgranular zone (SGZ) …
Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model
Y Yu, J He, Y Zhang, H Luo, S Zhu, Y Yang… - …, 2009 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with
senile β‐amyloid (Aβ) plaques and cognitive decline. Neurogenesis in the adult …
senile β‐amyloid (Aβ) plaques and cognitive decline. Neurogenesis in the adult …
Limited hippocampal neurogenesis in SAMP8 mouse model of Alzheimer's disease
B Gang, C Yue, N Han, H Xue, B Li, L Sun, X Li, Q Zhao - Brain research, 2011 - Elsevier
Increasing adult neurogenesis in the hippocampal formation (HF) has been proposed as a
potential foundation for neuronal repair in Alzheimer's disease (AD), but the evidence …
potential foundation for neuronal repair in Alzheimer's disease (AD), but the evidence …
[HTML][HTML] Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease
X Zhang, X Wei, Y Mei, D Wang, J Wang, Y Zhang, X Li… - Stem cell reports, 2021 - cell.com
New neurons are abnormal in the adult hippocampus of Alzheimer's disease (AD) mouse
models. The effects of modulating adult neurogenesis on AD pathogenesis differ from study …
models. The effects of modulating adult neurogenesis on AD pathogenesis differ from study …
Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw, Ind) mice
Formation and accumulation of amyloid-beta (Aβ) plaques are associated with declined
memory and other neurocognitive function in Alzheimer's disease (AD) patients. However …
memory and other neurocognitive function in Alzheimer's disease (AD) patients. However …
[HTML][HTML] Valproic Acid Stimulates Hippocampal Neurogenesis via Activating the Wnt/β-Catenin Signaling Pathway in the APP/PS1/Nestin-GFP Triple Transgenic …
Q Zeng, Z Long, M Feng, Y Zhao, S Luo… - Frontiers in aging …, 2019 - frontiersin.org
Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by the
deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of …
deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of …
Noggin and BMP4 co-modulate adult hippocampal neurogenesis in the APPswe/PS1ΔE9 transgenic mouse model of Alzheimer's disease
J Tang, M Song, Y Wang, X Fan, H Xu, Y Bai - Biochemical and biophysical …, 2009 - Elsevier
In addition to the subventricular zone, the dentate gyrus of the hippocampus is one of the
few brain regions in which neurogenesis continues into adulthood. Perturbation of …
few brain regions in which neurogenesis continues into adulthood. Perturbation of …
[HTML][HTML] Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer's disease by compromising hippocampal inhibition
Background The molecular mechanism underlying progressive memory loss in Alzheimer's
disease is poorly understood. Neurogenesis in the adult hippocampus is a dynamic process …
disease is poorly understood. Neurogenesis in the adult hippocampus is a dynamic process …
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