Amyotrophic lateral sclerosis/motor neuron disease is a severe neurodegenerative disease
characterized by upper and lower motor neuron degeneration for which there is no truly …

Opinion statement More than a century after its initial clinicopathologic description,
amyotrophic lateral sclerosis (ALS) remains a largely fatal, progressive neurodegenerative …

Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …

Motor neuron diseases are mostly degenerative disorders that result in disability from
weakness and wasting of muscle. Amyotrophic lateral sclerosis (ALS), often referred to …

Amyotropic lateral sclerosis (ALS) is a progressive degenerative condition of motor neurons
that is ultimately fatal. Even though scientific discovery over the past few decades has led to …

ALS is a lethal neurodegenerative disease wherein the diagnosis is often delayed. Our
understanding of the pathobiology is slowly expanding, and the number of new genes is …

Background: Riluzole is the most widespread therapeutic for treatment of the progressive
degenerative disease amyotrophic lateral sclerosis (ALS). Riluzole gained FDA approval in …

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of upper and lower
motor neurons (MNs) leading to paralysis and, ultimately, death by respiratory failure 3–5 …

Amyotrophic lateral sclerosis (ALS) is a clinically severe and fatal neurodegenerative
disease characterized by a loss of both upper and lower motor neurons, resulting in …

Because treatments are not yet powerful enough to reverse the symptoms of amyotrophic
lateral sclerosis (ALS), randomized placebo-controlled trials remain the gold standard for …