Dendritic cells as regulators of the immune response to inhaled allergen: recent findings in animal models of asthma

BN Lambrecht, HC Hoogsteden… - International archives of …, 2001 - karger.com
Antigen-presenting dendritic cells are essential for the recognition and presentation of
allergens to the cells of the immune system. Airway dendritic cells capture allergen in the …

Dendritic cells revisited in human allergic rhinitis and asthma

A Froidure, C Shen, C Pilette - Allergy, 2016 - Wiley Online Library
The role of dendritic cells (DC s) in airway allergy has been studied for 15 years; recent data
has highlighted the cross talk with airway epithelial cells and environmental factors …

Dendritic cells in asthma: a function beyond sensitization

LS Van Rijt, BN Lambrecht - Clinical & Experimental Allergy, 2005 - Wiley Online Library
Allergic asthma is one of the most common chronic diseases in western society,
characterized by variable airway obstruction, mucus hypersecretion and infiltration of the …

Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma

H Hammad, BN Lambrecht - Nature Reviews Immunology, 2008 - nature.com
Dendritic cells (DCs) are generally held responsible for initiating and maintaining allergic T
helper 2 (TH2)-cell responses to inhaled allergens in asthma. Although the epithelium was …

The other cells in asthma: dendritic cell and epithelial cell crosstalk

BN Lambrecht, H Hammad - Current opinion in pulmonary …, 2003 - journals.lww.com
Dendritic cells (DCs) and epithelial cells are the first cells to encounter inhaled allergens.
The response of these cell types to allergens is fundamentally different in asthmatics …

Human dendritic cells in allergic asthma and rhinitis

A Froidure, C Pilette - Medecine Sciences: M/S, 2015 - europepmc.org
The role of dendritic cells (DC) in the pathogenesis of allergic asthma and rhinitis has been
highlighted for 15 years. In this review, we summarize key findings concerning DC function …

Dendritic cells in asthma

MJ van Helden, BN Lambrecht - Current opinion in immunology, 2013 - Elsevier
Highlights•Dendritic cells (DCs) are essential for inducing Th2 immunity to several
allergens.•Similar to other organs, lung DCs are a heterogeneous population of …

Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses

H Hammad, BN Lambrecht - Allergy, 2011 - Wiley Online Library
To cite this article: Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at
the interface between innate and adaptive immune responses. Allergy 2011; 66: 579–587 …

Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

H Hammad, BN Lambrecht - Journal of allergy and clinical immunology, 2006 - Elsevier
Dendritic cells (DCs) are crucial in determining the outcome of antigen encounter and
integrating signals derived from the antigen, its inflammatory context, and the host …

Why are dendritic cells important in allergic diseases of the respiratory tract?

JW Upham, PA Stumbles - Pharmacology & therapeutics, 2003 - Elsevier
Increasing evidence points to the role of antigen-presenting dendritic cells (DC) in regulating
adaptive immune responses. DC are especially sensitive to signals derived from microbes …