Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development

TL Rankin, M O'Brien, E Lee, K Wigglesworth… - …, 2001 - journals.biologists.com
All vertebrate eggs are surrounded by an extracellular matrix. This matrix is known as the
zona pellucida in mammals and is critically important for the survival of growing oocytes …

Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile

T Rankin, M Familari, E Lee, A Ginsberg… - …, 1996 - journals.biologists.com
Mammalian oocytes synthesize and secrete a zona pellucida that surrounds the growing
oocytes, ovulated eggs and preimplantation embryos. The extracellular zona matrix is …

Four zona pellucida glycoproteins are expressed in the human

L Lefièvre, SJ Conner, A Salpekar… - Human …, 2004 - academic.oup.com
BACKGROUND: The zona pellucida (ZP) is an extracellular glycoprotein matrix which
surrounds all mammalian oocytes. Recent data have shown the presence of four human …

Immunohistochemical localization of zona pellucida proteins ZPA, ZPB and ZPC in human, cynomolgus monkey and mouse ovaries

U Eberspaecher, A Becker, P Bringmann… - Cell and Tissue …, 2001 - Springer
The zona pellucida of mammalian oocytes plays an important role in binding and activation
of sperm cells during the molecular events leading to fertilization. The genes coding for the …

[HTML][HTML] Sequence variations in human ZP genes as potential modifiers of zona pellucida architecture

RM Pökkylä, JT Lakkakorpi, SH Nuojua-Huttunen… - Fertility and sterility, 2011 - Elsevier
To examine putative associations between zona pellucida (ZP) anomalies and sequence
variations in genes expressing structural ZP glycoprotein components, sequence data of 31 …

Features that affect secretion and assembly of zona pellucida glycoproteins during mammalian oogenesis.

L Jovine, H Qi, Z Williams, ES Litscher… - … of Reproduction and …, 2007 - europepmc.org
For sperm to fertilize eggs, they must bind to and penetrate the zona pellucida (ZP) that
surrounds the plasma membrane of all mammalian eggs. The ZP first appears during oocyte …

The mouse egg's zona pellucida

PM Wassarman, ES Litscher - Current topics in developmental biology, 2018 - Elsevier
All mammalian eggs are surrounded by a highly specialized extracellular matrix (ECM),
called the zona pellucida (ZP), that functions before, during, and after fertilization. Unlike …

[PDF][PDF] Mammalian fertilization: the egg's multifunctional zona pellucida

PM Wassarman, ES Litscher - International Journal of Developmental …, 2008 - unite.it
The zona pellucida (ZP) is a specialized extracellular coat that surrounds the plasma
membrane of mammalian eggs. Its presence is essential for successful completion of …

Genomic mapping of murine Zp-2 and Zp-3, two oocyte-specific loci encoding zona pellucida proteins

RD Lunsford, NA Jenkins, CA Kozak, L Liang, CM Silan… - Genomics, 1990 - Elsevier
The zona pellucida is a unique, oocyte-specific matrix that coats the surface of all
mammalian eggs. Composed of three sulfated glycoproteins in the mouse (ZP1, ZP2, and …

Mouse Zp1 encodes a zona pellucida protein homologous to egg envelope proteins in mammals and fish

O Epifano, L Liang, J Dean - Journal of Biological Chemistry, 1995 - ASBMB
Zp1 encodes one of the three major glycoproteins of the zona pellucida, an extracellular
matrix that surrounds growing oocytes, ovulated eggs, and preimplantation embryos. The …