The mammalian zona pellucida surrounding ovulated eggs mediates sperm binding at
fertilization, provides a postfertilization block to polyspermy, and facilitates passage of pre …

The zona pellucida is an extracellular coat that surrounds mammalian eggs and early
embryos. This insoluble matrix separates germ from somatic cells during folliculogenesis …

Fertilization requires taxon-specific gamete recognition, and human sperm do not bind to
zonae pellucidae (ZP1–3) surrounding mouse eggs. Using transgenesis to replace …

BACKGROUND It has been suggested that the zona pellucida (ZP) may mediate species-
specific fertilization. In human the ZP is composed of four glycoproteins: ZP1, ZP2, ZP3 and …

The zona pellucida (ZP) is the extracellular matrix that plays important roles in sperm-egg
interaction. The ZP is composed of three major glycoproteins that exhibit heterogeneity due …

Many studies of the molecular and biochemical aspects of mammalian fertilization have
focused on the interaction of the spermatozoa with the zona pellucida (ZP). The zona …

A cDNA (rc75) encoding a 75-kDa rabbit zona pellucida (ZP) glycoprotein (R75) has been
cloned and sequenced. The predicted amino acid sequence consists of 676 amino acids …

The zona pellucida (ZP) glycoproteins play an important role in oocyte development and
gamete biology. To analyze their expression in follicles during various developmental …

The mouse zona pellucida protein ZP2 plays an important role in the process of fertilization
by mediating secondary sperm binding to mammalian oocytes. ZP2 primary structures are …

Purpose We aimed to identify pathogenic variants in two infertile sisters in a family with a
thin zona pellucida (ZP) phenotype. Methods Whole-exome sequencing was performed in …