Investigation of the effect of discrete absorbers upon the measurement of blood volume with near-infrared spectroscopy

M Firbank, E Okada, DT Delpy - Physics in Medicine & Biology, 1997 - iopscience.iop.org
This paper derives an analytical model for investigating the effect of the distribution of
absorbers upon light attenuation in a scattering medium. Results from this are found to …

Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy?

DA Boas, G Strangman, JP Culver… - Physics in Medicine …, 2003 - iopscience.iop.org
We have measured the changes in oxy-haemoglobin and deoxy-haemoglobin in the adult
human brain during a brief finger tapping exercise using near-infrared spectroscopy (NIRS) …

Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation

S Wray, M Cope, DT Delpy, JS Wyatt… - Biochimica et Biophysica …, 1988 - Elsevier
Near infrared (IR) spectroscopy can give continuous, direct information about cerebral
oxygenation in vivo by providing signals from oxygenated and deoxygenated haemoglobin …

Data analysis methods for near-infrared spectroscopy of tissue: problems in determining the relative cytochrome aa3 concentration

M Cope, P van der Zee, M Essenpreis… - … and Imaging of …, 1991 - spiedigitallibrary.org
In the brain of the adult rat, the ratio of the absorption coefficient of hemoglobin to that of the
cytochromes is approximately ten and in the newborn rat brain the ratio is even higher …

Assessment of local brain activation: A simultaneous PET and near-infrared spectroscopy study

K Villringer, S Minoshima, C Hock, H Obrig… - Optical Imaging of Brain …, 1997 - Springer
In five healthy human subjects, near-infrared spectroscopy (NIRS) and positron emission
tomography (PET) examinations were performed simultaneously. Changes in [oxy …

Quantitation of pathlength in optical spectroscopy

DT Delpy, SR Arridge, M Cope, D Edwards… - Oxygen Transport to …, 1989 - Springer
The relative transparency of tissues to near infrared light means that it is possible to
transilluminate intact organs. In the infrared region, oxygen dependent absorptions due to …

The effect of optode positioning on optical pathlength in near infrared spectroscopy of brain

P Van der Zee, SR Arridge, M Cope… - Oxygen transport to tissue …, 1990 - Springer
The use of optical spectroscopy for the non-invasive monitoring of tissue oxygenation and
metabolism is well established (Chance et al., 1975). Historically because of the high …

Non-invasive optical spectroscopy and imaging of human brain function

A Villringer, B Chance - Trends in neurosciences, 1997 - cell.com
Brain activity is associated with changes in optical properties of brain tissue. Optical
measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c …

Cognition-activated low-frequency modulation of light absorption in human brain.

B Chance, Z Zhuang, C UnAh… - Proceedings of the …, 1993 - National Acad Sciences
Animal model studies indicate light-absorption changes of the exposed animal brain in
response to visual stimulation. Here we report observations of red-light absorbance …

An investigation of light transport through scattering bodies with non-scattering regions

M Firbank, SR Arridge, M Schweiger… - Physics in Medicine & …, 1996 - iopscience.iop.org
An investigation of light transport through scattering bodies with non-scattering regions Page 1
Physics in Medicine & Biology An investigation of light transport through scattering bodies with …