Spectroscopic analysis of changes in remitted illumination: the response to increased neural activity in brain

J Mayhew, Y Zheng, Y Hou, B Vuksanovic, J Berwick… - Neuroimage, 1999 - Elsevier
Imaging of neural activation has been used to produce maps of functional architecture and
metabolic activity. There is some uncertainty associated with the sources underlying the …

Near-infrared oxymeter prototype for noninvasive analysis of rat brain oxygenation

F Crespi, M Donini, A Bandera, C Heidbreder… - Optical …, 2004 - spiedigitallibrary.org
The feasibility of non-invasive analysis of brain activities was studied in the attempt to
overcome the major limitation of actual in vivo methodologies ie invasiveness. Optic fibre …

Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics

JR Mourant, JP Freyer, AH Hielscher, AA Eick… - Applied …, 1998 - opg.optica.org
We have studied the optical properties of mammalian cell suspensions to provide a
mechanistic basis for interpreting the optical properties of tissues in vivo. Measurements of …

Somatosensory evoked fast optical intensity changes detected non-invasively in the adult human head

J Steinbrink, M Kohl, H Obrig, G Curio, F Syre… - Neuroscience …, 2000 - Elsevier
This work is the first to report optical intensity changes (ΔI/I≈ 0.05%) with a latency between
60 and 160ms after electrical median nerve stimulation at 5Hz detected non-invasively …

Broad bandwidth frequency domain instrument for quantitative tissue optical spectroscopy

TH Pham, O Coquoz, JB Fishkin, E Anderson… - Review of scientific …, 2000 - pubs.aip.org
Near-infrared (NIR) optical properties of turbid media, eg, tissue, can be accurately
quantified noninvasively using methods based on diffuse reflectance or transmittance, such …

[PDF][PDF] The application of near infrared spectroscopy to non invasive monitoring of cerebral oxygenation in the newborn infant

M Cope - Department of Medical Physics and Bioengineering, 1991 - Citeseer
This project had two main objectives. The first of these was to design and construct a
spectroscopic instrument to monitor small changes in optical transmission across an infant's …

Frequency-domain optical absorption spectroscopy of finite tissue volumes using diffusion theory

BW Pogue, MS Patterson - Physics in medicine & biology, 1994 - iopscience.iop.org
The goal of frequency-domain optical absorption spectroscopy is the noninvasive
determination of the absorption coefficient of a specific tissue volume. Since this allows the …

Determination of reduced scattering coefficient of biological tissue from a needle-like probe

M Johns, CA Giller, DC German, H Liu - Optics express, 2005 - opg.optica.org
Detection of interactions between light and tissue can be used to characterize the optical
properties of the tissue. The purpose of this paper is to develop an algorithm that determines …

In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model

A Kienle, T Glanzmann - Physics in Medicine & Biology, 1999 - iopscience.iop.org
We have investigated the possibility of determining the optical coefficients of muscle in the
extremities with in vivo time-resolved reflectance measurements using a layered model. A …

Near-infrared monitoring of cerebral oxygen sufficiency: I. Spectra of cytochrome c oxidase

FF Jöbsis-VanderVliet, CA Piantadosi… - Neurological …, 1988 - Taylor & Francis
Near-infrared (NIR) difference spectra were obtained for oxidized cytochrome c oxidase of
isolated mitochondria in vitro and of cerebral tissue in situ observed through scalp and skull …