Objectives: Guidelines recommend use of norepinephrine as the first-line treatment for fluid-
refractory septic shock and if septic shock persists vasopressin may be initiated. Since there …

Septic shock is associated with a relative deficiency of the endogenous stress hormone
vasopressin. In shock states vasopressin binds to vasopressin receptors on vascular smooth …

Rationale: Vasopressin may be used to treat vasodilatory hypotension in septic shock, but it
is not recommended by guidelines as a first-or second-line agent. Little is known about how …

Abstract Study Objective Significant practice variation exists when selecting between
hydrocortisone and vasopressin as second line agents in patients with septic shock in need …

Septic shock continues to be one of the leading causes of death in the intensive care unit
today. The confluence of many factors contributes to the deterioration of patients' condition in …

BACKGROUND: Consensus guidelines suggested that both dopamine and norepinephrine
may be used, but specific doses are not recommended. The aim of this study is to determine …

Background: Vasopressin decreases vasopressor requirements in patients with septic
shock. However, the optimal norepinephrine dose for initiation or cessation of vasopressin is …

Context Given the high mortality of 30%–60% associated with septic shock, distinguishing
which patients do or do not have a reasonable chance of surviving with aggressive …

Arginine vasopressin (AVP) and its synthetic, long-acting analog terlipressin (TP) are potent
alternative vasoconstrictors in the treatment of septic patients with catecholamine-refractive …