The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), like other coronaviruses,
replicates their genome in virus-induced cytosolic membrane-bound replication organelles …
replicates their genome in virus-induced cytosolic membrane-bound replication organelles …
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiologic agent for the
global COVID-19 pandemic, triggers the formation of endoplasmic reticulum (ER)-derived …
global COVID-19 pandemic, triggers the formation of endoplasmic reticulum (ER)-derived …
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles
A Kratzel, V Thiel - Journal of Cell Biology, 2023 - rupress.org
SARS-CoV-2 depends on host proteins for successful replication. In this issue, Williams et
al.(2023. J. Cell Biol. https://doi. org/10.1083/jcb. 202203060) report that the ER membrane …
al.(2023. J. Cell Biol. https://doi. org/10.1083/jcb. 202203060) report that the ER membrane …
[HTML][HTML] Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remodels the endoplasmic
reticulum (ER) to form replication organelles, leading to ER stress and unfolded protein …
reticulum (ER) to form replication organelles, leading to ER stress and unfolded protein …
Identification of host dependency factors involved in SARS-CoV-2 replication organelle formation through proteomics and ultrastructural analysis
F Pahmeier, TM Lavacca, S Goellner… - Journal of …, 2023 - Am Soc Microbiol
Positive-strand RNA viruses subvert the cellular endomembrane system for the generation
of distinct compartments termed replication organelles (ROs) that harbor the site where viral …
of distinct compartments termed replication organelles (ROs) that harbor the site where viral …
Molecular mechanisms for understanding the association between TMPRSS2 and beta coronaviruses SARS-CoV-2, SARS-CoV and MERS-CoV infection: Scoping …
MJ Chaves-Medina, JC Gomez-Ospina… - Archives of …, 2022 - Springer
The aim of this scoping review was to identify knowledge gaps and to describe the current
state of the research on the association between TMPRSS2 and the essential beta …
state of the research on the association between TMPRSS2 and the essential beta …
The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle
S Ricciardi, AM Guarino, L Giaquinto, EV Polishchuk… - Nature, 2022 - nature.com
Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …
EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8
Y Zhao, L Sui, P Wu, L Li, L Liu, B Ma, W Wang… - Journal of …, 2023 - Am Soc Microbiol
Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has led to an unprecedented public health crisis worldwide. Though the host …
(SARS-CoV-2), has led to an unprecedented public health crisis worldwide. Though the host …
TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution
The accessory protease transmembrane protease serine 2 (TMPRSS2) enhances severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uptake into ACE2-expressing …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uptake into ACE2-expressing …
TMPRSS11D and TMPRSS13 activate the SARS-CoV-2 spike protein
M Kishimoto, K Uemura, T Sanaki, A Sato, WW Hall… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) utilizes host proteases,
including a plasma membrane-associated transmembrane protease, serine 2 (TMPRSS2) to …
including a plasma membrane-associated transmembrane protease, serine 2 (TMPRSS2) to …