Matrine: Bioactivities and structural modifications

J Huang, H Xu - Current Topics in Medicinal Chemistry, 2016 - ingentaconnect.com
Matrine is a quinolizidine alkaloid isolated from the roots of Sophora flavescens (Kushen),
Sophora tonkinensis, and Sophora alopecuroides (Kudouzi). Matrine and its derivatives …

[HTML][HTML] Research progress of natural matrine compounds and synthetic matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

[HTML][HTML] Matrine family derivatives: Synthesis, reactions procedures, mechanism, and application in medicinal, agricultural, and materials chemistry

JAH Kowah, R Gao, F Li, C Guang, M Jiang… - European Journal of …, 2023 - Elsevier
Matrine alkaloid is a type of Sophora flavescens (Ku Shen) found in plants. It holds excellent
applications for anticancer, antimicrobials, antibacterial, anti pests, and other applications in …

[HTML][HTML] Matrine: a promising natural product with various pharmacological activities

H Zhang, L Chen, X Sun, Q Yang, L Wan… - Frontiers in …, 2020 - frontiersin.org
Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Structural modifications of matrine-type alkaloids

XH Cai, H Guo, B Xie - Mini Reviews in Medicinal Chemistry, 2018 - ingentaconnect.com
Matrine-type alkaloids belong to quinolizidine analogues from Sophora flavescens Ait,
Sophora subprostrata and Sophora alopecuroides L. possess numerous therapeutic …

Anticancer advances of matrine and its derivatives

J Yong, X Wu, C Lu - Current pharmaceutical design, 2015 - ingentaconnect.com
As the second leading cause of death in the world, the total number caused by cancer in
2008 is 1.4 million. The great cancer incidence worldwide increases the search for new …

[HTML][HTML] Synthesis, characterization and in vitro biological evaluation of two matrine derivatives

X Cheng, J Ye, H He, Z Liu, C Xu, B Wu, X Xiong… - Scientific Reports, 2018 - nature.com
Matrine is a traditional Chinese medicine and botanical pesticide with broad biological
activities, including pharmacological and agricultural activities. In present work, two matrine …

Research advances on anticancer activities of matrine and its derivatives: An updated overview

H ur Rashid, Y Xu, Y Muhammad, L Wang… - European journal of …, 2019 - Elsevier
Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

[HTML][HTML] A systematic review of the pharmacology, toxicology and pharmacokinetics of matrine

L You, C Yang, Y Du, W Wang, M Sun, J Liu… - Frontiers in …, 2020 - frontiersin.org
Matrine (MT) is a naturally occurring alkaloid and an bioactive component of Chinese herbs,
such as Sophora flavescens and Radix Sophorae tonkinensis. Emerging evidence suggests …

Research progress of matrine's anticancer activity and its molecular mechanism

F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
Background and ethnopharmacological relevance: Matrine (MT), a type of alkaloid extracted
from the Sophora family of traditional Chinese medicine, has been documented to exert a …