[HTML][HTML] Matrine induces papillary thyroid cancer cell apoptosis in vitro and suppresses tumor growth in vivo by downregulating miR-182-5p

S Fu, N Zhao, G Jing, X Yang, J Liu, D Zhen… - Biomedicine & …, 2020 - Elsevier
Matrine is a natural product extracted from the root of Sophora flavescens that has been
shown to be a promising alternative drug in different types of cancer. Here, we aimed to …

Agrochemical properties evaluation of some imines alkaloids of matrine/oxymatrine

M Lv, Q Ma, S Zhang, H Xu - Bioorganic & Medicinal Chemistry Letters, 2021 - Elsevier
To discover non-food renewable forest bioactive products as new potential pesticidal
alternatives for crop protection, a series of C15-imines alkaloids were obtained by structural …

Oxymatrine targets EGFRp-Tyr845 and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells

B Guo, T Zhang, J Su, K Wang, X Li - Cancer chemotherapy and …, 2015 - Springer
Purpose Oxymatrine (matrine oxide, matrine N-oxide, matrine 1-oxide) is one of the
quinolizidine alkaloid compounds extracted from the root of Sophora flavescens (a …

Chemical and bioactive diversities of the genera Stachybotrys and Memnoniella secondary metabolites

A Wang, Y Xu, Y Gao, Q Huang, X Luo, H An… - Phytochemistry …, 2015 - Springer
During the course of search for novel and bioactive molecules of microbial origin for drug
development, Stachybotrys and Memnoniella fungi generally have been found to be a rich …

[HTML][HTML] Matrine effectively inhibits the proliferation of breast cancer cells through a mechanism related to the NF‑κB signaling pathway

H Shao, B Yang, R Hu, Y Wang - Oncology letters, 2013 - spandidos-publications.com
Matrine is an alkaloid isolated from Sophora flavescens. The present study aimed to
determine whether matrine effectively inhibits the proliferation of breast cancer cells, and the …

[HTML][HTML] Effects of matrine on the proliferation of HT29 human colon cancer cells and its antitumor mechanism

C Chang, SP Liu, CH Fang, RS He… - Oncology …, 2013 - spandidos-publications.com
Matrine is one of the main active components that is extracted from the dry roots of Sophora
flavescens. The compound has potent antitumor activity in various cancer cell lines …

Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells

S Zhang, J Qi, L Sun, B Cheng, S Pan, M Zhou… - Molecular Biology …, 2009 - Springer
Matrine, one of the main components extracted from Sophora flavescens Ait, has a wide
range of pharmacological effects including anti-tumor activities on a number of cancer cell …

Oxymatrine: A current overview of its health benefits

DQ Huan, NQ Hop, NT Son - Fitoterapia, 2023 - Elsevier
Oxymatrine (OMT), was identified as a quinolizidine alkaloid, which was one of the major
matrine-type alkaloids extracted from Sophora medicinal plants. Growing studies revealed …

Quinolizidine alkaloids from the roots of Sophora flavescens

JC Li, ZJ Zhang, D Liu, MY Jiang, RT Li… - Natural Product …, 2022 - Taylor & Francis
Seventeen quinolizidine alkaloids, including a new matrine-type one, sophcence A (1), were
isolated from the roots of Sophora flavescens Alt. The structure of compound 1 was …

[HTML][HTML] Structural classification and biological activities of Stemona alkaloids

H Greger - Phytochemistry reviews, 2019 - Springer
Stemona alkaloids represent a unique class of natural products exclusively known from the
three genera Stemona, Stichoneuron, and Croomia of the monocotyledonous family …