Oxymatrine Extracted from Sophora flavescens Inhibited Cell Growth and Induced Apoptosis in Human Osteosarcoma MG-63 Cells In Vitro

J Wei, Y Zhu, G Xu, F Yang, Z Guan, M Wang… - Cell biochemistry and …, 2014 - Springer
Oxymatrine, one of the most active components of the ethanol extracts from Sophora
flavescens, is known for its potent antitumor activity both in vitro and in vivo. However, the …

Stemona Alkaloids: Biosynthesis, Classification, and Biogenetic Relationships

FP Wang, QH Chen - Natural Product Communications, 2014 - journals.sagepub.com
Stemona alkaloids form a unique class, which can be attributed to hemiterpenoid pyrrolidine-
and monoterpenoid pyrrolidine-class alkaloids originated from L-ornithine and glutamic …

Mesua beccariana (Clusiaceae), A Source of Potential Anti-cancer Lead Compounds in Drug Discovery

SS Teh, G Cheng Lian Ee, SH Mah, YM Lim… - Molecules, 2012 - mdpi.com
An investigation on biologically active secondary metabolites from the stem bark of Mesua
beccariana was carried out. A new cyclodione, mesuadione (1), along with several known …

Biological effects and mechanisms of matrine and other constituents of Sophora flavescens in colorectal cancer

MH Chen, YY Gu, AL Zhang, DM Sze, SL Mo… - Pharmacological …, 2021 - Elsevier
Abstract The plant Sophora flavescens Ait. has been used in the clinical management of
colorectal cancer (CRC). Its constituent compounds, notably the alkaloids matrine …

Discovery of luotonin A analogues as potent fungicides and insecticides: Design, synthesis and biological evaluation inspired by natural alkaloid

GZ Yang, J Zhang, JW Peng, ZJ Zhang… - European Journal of …, 2020 - Elsevier
The prevention and control of plant diseases and insect pests is the most crucial issue facing
crop protection. To discover novel pesticide candidates with diverse chemical structures …

Steroidal alkaloids from Solanum nigrum and their cytotoxic activities

LY Liu, YK Yang, JN Wang, JG Ren - Phytochemistry, 2022 - Elsevier
Eight undescribed, along with five known steroidal alkaloids were isolated from Solanum
nigrum L., a plant used in traditional Chinese medicine. Their structures were elucidated by …

Pharmacokinetic characterization of oxymatrine and matrine in rats after oral administration of radix Sophorae tonkinensis extract and oxymatrine by sensitive and …

L Tang, LN Dong, XJ Peng, Y Li, J Shi, FY Zhou… - … of pharmaceutical and …, 2013 - Elsevier
The purpose of this study is to systematically investigate the pharmacokinetic (PK) behaviors
of radix Sophorae tonkinensis (S. tonkinensis) using oxymatrine (OMT) and matrine (MT) as …

[HTML][HTML] Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicological effects of Mimosa pudica-A review

OE Adurosakin, EJ Iweala, JO Otike, ED Dike… - Pharmacological …, 2023 - Elsevier
Introduction Mimosa pudica L. is a creeping herbaceous ornamental plant belonging to the
Mimosaceae family. It is used in ethnomedicine to prevent or treat various illnesses like …

Pharmacology, toxicology, and metabolism of sennoside A, A medicinal plant-derived natural compound

J Le, H Ji, X Zhou, X Wei, Y Chen, Y Fu, Y Ma… - Frontiers in …, 2021 - frontiersin.org
Sennoside A (SA) is a natural dianthrone glycoside mainly from medicinal plants of Senna
and Rhubarb, and used as a folk traditional irritant laxative and slimming health food …

Nematicidal Stemona Alkaloids from Stemona parviflora

SZ Huang, FD Kong, QY Ma, ZK Guo… - Journal of Natural …, 2016 - ACS Publications
Eight new alkaloids, 3β-n-butylstemonamine (1), 8-oxo-3β-n-butylstemonamine (2), 3-n-
butylneostemonine (3), 10-epi-3-n-butylneostemonine (4), 8-oxo-oxymaistemonine (5) …