A glimpse into past, present, and future DNA sequencing
M Morey, A Fernández-Marmiesse… - Molecular genetics and …, 2013 - Elsevier
Current advances in DNA sequencing technologies are dropping down sequencing cost
while increasing throughput at a pace never shown before. Past-decade great milestones …
while increasing throughput at a pace never shown before. Past-decade great milestones …
Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issues
N Hallowell, A Hall, C Alberg, R Zimmern - Journal of Medical Ethics, 2015 - jme.bmj.com
The introduction of new sequencing technologies whole-genome sequencing (WGS) and
whole-exome sequencing (WES) that are much less finely targeted than previous genetic …
whole-exome sequencing (WES) that are much less finely targeted than previous genetic …
The importance of genetic counselling in genome-wide sequencing
AM Elliott, JM Friedman - Nature Reviews Genetics, 2018 - nature.com
Genome-wide sequencing (GWS) is the most sensitive test available for detecting
pathogenic genetic variants. In line with guidelines in North America and Europe, best …
pathogenic genetic variants. In line with guidelines in North America and Europe, best …
[引用][C] Imagined futures: capturing the benefits of genome sequencing for society
B Capps, R Chadwick, D Chalmers, A Clarke… - 2013 - figshare.utas.edu.au
This White Paper aims to explore the key ethical issues arising from genome sequencing in
light of the rapid advances in sequencing technology which will result in faster, more …
light of the rapid advances in sequencing technology which will result in faster, more …
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY …
Background There is tremendous potential for genome sequencing to improve clinical
diagnosis and care once it becomes routinely accessible, but this will require formalizing …
diagnosis and care once it becomes routinely accessible, but this will require formalizing …
Sequencing your genome: your future is here, but are you sure you want to know it?
Next-generation sequencing (NGS; also known as deep sequencing or ultra-high
throughput sequencing) has probably been the most important tool for genomic research …
throughput sequencing) has probably been the most important tool for genomic research …
Challenges in the clinical application of whole-genome sequencing
As the cost of sequencing the human genome falls, medical use of whole-genome
sequencing will rapidly advance. 1 In this Viewpoint, we consider the opportunities and …
sequencing will rapidly advance. 1 In this Viewpoint, we consider the opportunities and …
Living laboratory: whole‐genome sequencing as a learning healthcare enterprise
M Angrist, L Jamal - Clinical Genetics, 2015 - Wiley Online Library
With the proliferation of affordable large‐scale human genomic data come profound and
vexing questions about management of such data and their clinical uncertainty. These …
vexing questions about management of such data and their clinical uncertainty. These …
Recommendations for whole genome sequencing in diagnostics for rare diseases
In 2016, guidelines for diagnostic Next Generation Sequencing (NGS) have been published
by EuroGentest in order to assist laboratories in the implementation and accreditation of …
by EuroGentest in order to assist laboratories in the implementation and accreditation of …