Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides
B Kavanagh, A Ko, A Venook, K Margolin… - Journal of …, 2007 - journals.lww.com
Developing a process to generate dendritic cells (DCs) applicable for multicenter trials
would facilitate cancer vaccine development. Moreover, targeting multiple antigens with …
would facilitate cancer vaccine development. Moreover, targeting multiple antigens with …
Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive …
A Tamir, E Basagila, A Kagahzian, L Jiao… - Cancer Immunology …, 2007 - Springer
Abstract Background Dendritic cells (DCs) are the most effective antigen-presenting cells. In
the last decade, the use of DCs for immunotherapy of cancer patients has been vastly …
the last decade, the use of DCs for immunotherapy of cancer patients has been vastly …
Dendritic cell‐based cancer immunotherapy: Potential for treatment of colorectal cancer?
Human tumours including those of the gastrointestinal tract express a number of specific
antigens that can be recognized by T cells, thus providing potential targets for cancer …
antigens that can be recognized by T cells, thus providing potential targets for cancer …
Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded …
J Babatz, C Röllig, B Löbel, G Folprecht… - Cancer Immunology …, 2006 - Springer
Abstract Purpose: Dendritic cells (DCs) are characterized by their extraordinary capacity to
induce T-cell responses, providing the opportunity of DC-based cancer vaccination …
induce T-cell responses, providing the opportunity of DC-based cancer vaccination …
Comparison of monocyte-derived dendritic cells from colorectal cancer patients, non-small-cell-lung-cancer patients and healthy donors
P Kvistborg, CM Bechmann, AW Pedersen, HC Toh… - Vaccine, 2009 - Elsevier
Dendritic cells (DCs) are bone marrow-derived professional antigen presenting cells. Due to
their role as potent inducers of immune responses, these cells are widely used as adjuvant …
their role as potent inducers of immune responses, these cells are widely used as adjuvant …
Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic …
M Sakakibara, T Kanto, M Hayakawa, S Kuroda… - Cancer Immunology …, 2011 - Springer
Dendritic cell (DC) vaccine has been used to treat patients with advanced colorectal cancer
(CRC). The results of vaccine-induced clinical responses have not always been satisfactory …
(CRC). The results of vaccine-induced clinical responses have not always been satisfactory …
Generation of carcinoembryonic antigen (CEA)-specific T-cell responses in HLA-A* 0201 and HLA-A* 2402 late-stage colorectal cancer patients after vaccination with …
KJ Liu, CC Wang, LT Chen, AL Cheng, DT Lin… - Clinical cancer …, 2004 - AACR
Purpose: We intranodally immunized metastatic colorectal carcinoma patients, who had
failed standard chemotherapy, with dendritic cells (DCs) pulsed with HLA-A* 0201-or HLA …
failed standard chemotherapy, with dendritic cells (DCs) pulsed with HLA-A* 0201-or HLA …
Clinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccine
SK Burgdorf, A Fischer, PS Myschetzky… - Oncology …, 2008 - spandidos-publications.com
Patients with disseminated colorectal cancer have a poor prognosis. Preliminary studies
have shown encouraging results from vaccines based on dendritic cells. The aim of this …
have shown encouraging results from vaccines based on dendritic cells. The aim of this …
Dendritic cell-based immunotherapy of cancer with carcinoembryonic antigen-derived, HLA-A24-restricted CTL epitope: Clinical outcomes of 18 patients with …
Y Ueda, T Itoh, I Nukaya… - International …, 2004 - spandidos-publications.com
We conducted a clinical study of cancer vaccine therapy with dendritic cells (DCs) and HLA-
A24-restricted carcinoembryonic antigen (CEA)-derived peptide to assess the feasibility and …
A24-restricted carcinoembryonic antigen (CEA)-derived peptide to assess the feasibility and …
Development of a dendritic cell (DC)-based vaccine for patients with advanced colorectal cancer.
N Rains, RJ Cannan, W Chen… - Hepato …, 2001 - europepmc.org
Results Flow cytometry confirmed dendritic cell phenotype and in vitro function was
confirmed by mixed lymphocyte reaction. No major adverse effects were observed. Eleven of …
confirmed by mixed lymphocyte reaction. No major adverse effects were observed. Eleven of …