Background. The significance of α-fetoprotein (AFP) messenger RNA as a surrogate marker
for isolated tumor cells in the blood of patients with hepatocellular carcinoma (HCC) is …

Hypothesis Isolated tumor cells may be associated with micrometastasis. Circulating α-
fetoprotein messenger RNA (AFP mRNA) in patients with hepatocellular carcinoma (HCC) …

Abstract α-fetoprotein (AFP) messenger RNA (mRNA) has been proposed as a marker of
hepatocellular carcinoma (HCC) cells disseminated into the circulation, but its clinical …

Purpose Intra-and extrahepatic recurrence is common, even after curative resection for
hepatocellular carcinoma (HCC), suggesting preoperative or intraoperative tumor cell …

Background: We tested for the presence of α‐fetoprotein (AFP) mRNA by using nested RT‐
PCR in the peripheral blood of hepatocellular carcinoma (HCC) patients who had …

Background/aims: Quantification of α 1-fetoprotein (AFP) mRNA in the blood using reverse
transcriptase polymerase chain reaction (RT-PCR) could be a useful tool in monitoring the …

OBJECTIVES Alpha-fetoprotein messenger RNA (AFP mRNA) in the peripheral blood (PB)
of patients with hepatocellular carcinoma (HCC) has been considered to represent isolated …

Abstract Purpose Detection of AFP mRNA in peripheral blood is considered a useful
predictor of HCC recurrence after resection. However, its interpretation and clinical …

Background/Aims: Since hematogenous spread of tumor cells may adversely affect the
prognosis of patients with hepatocellular carcinoma, we prospectively analyzed whether the …

In order to capture hepatocellular carcinoma (HCC) cells in circulating peripheral blood, we
made analysis to see if a-fetoprotein (AFP) mRNA exists in the peripheral blood obtained …