Background Antibiotic resistance in bacteria leads to massive health problems. Incidence of
carbapenem and multidrug resistance in Gram-negative bacteria are increasing globally …

Objectives: The increasing rate of carbapenem resistance in Gram-negative bacteria is a
major public health problem and rapid detection is essential for infection management. We …

Objectives Recently, matrix-assisted laser desorption ionization–time-of-flight mass
spectrometry (MALDI-TOF MS) was successfully applied for the detection of carbapenemase …

Carbapenemases should be accurately and rapidly detected, given their possible
epidemiological spread and their impact on treatment options. Here, we developed a simple …

Objectives Carbapenemase-resistant bacteria are increasingly spreading worldwide
causing public concern due to their ability to elude antimicrobial treatment. Early …

Laboratory identification of carbapenemase-producing clinical isolates is crucial to limit the
spread of the bacteria. In this study, we shall first develop the matrix-assisted laser …

Although carbapenemase-producing Enterobacteriaceae (CPE) have become a serious
public health issue, their detection remains challenging. The aim of this study was to …

Background Carbapenemase-producing gram-negative bacteria are increasing globally and
have been associated with outbreaks in hospital settings. Thus, the accurate detection of …

Abstract MALDI-TOF MS detection of carbapenemase-activity in Gram-negative bacteria was
compared against the Carba-NP assay. MALDI-TOF MS detected activity from 99% of the …

As carbapenemase-producing Gram-negative bacilli (CP-GNB)(Enterobacteriaceae,
Pseudomonadaceae, and Acinetobacter spp.) are becoming a major public health issue …