In order to explore which amino acids or which blocks of amino acids in the 29 amino acid
neuropeptide galanin are important for recognition of the endogenous ligand by galanin …

The neuropeptide galanin (1–29) binds with high affinity to hypothalamic receptors (KD∼
0.9 nM) and regulates feeding behavior. The N‐terminal fragments (1–16),(1–16) NH2 are …

Structure-activity studies demonstrate that galanin fragments 1-15 and 2-29 are fully active,
whereas fragment 3-29 has been reported to be inactive, in a number of different in vivo …

The hypothalamic galanin-like peptide (GALP) was isolated by its ability to activate galanin
receptors. The mature porcine GALP is a 60-amino acid neuropeptide proteolytically …

The galanin family currently consists of four peptides, namely galanin, galanin-message
associated peptide, galanin-like peptide and alarin. Unlike galanin that signals through …

Galanin, a 29–30-amino acid neuropeptide, is widely distributed in central and peripheral
systems and mediates a variety of physiological functions. Pharmacological studies have …

Synthetic fragments of galanin 1–29 were administered intraventricularly or into the
paraventricular nucleus of the hypothalamus for analysis of the critical amino acid sequence …

Galanin, a 29-amino acid peptide, is uniquely distributed in human basal forebrain and may
play a role in cholinergic cell dysfunction in Alzheimer's disease. We report a detailed …

The galanin neuropeptide system is widely distributed throughout the brain and periphery
and is thought to play a role in feeding, pain and reproduction. To evaluate the human …

Galanin receptors have been characterized in normal human hypothalamus using 125 I-
galanin binding assays. Competition experiments of porcine 125 I-galanin binding to human …