[HTML][HTML] Molecular genetics diversity of primary hemophagocytic lymphohistiocytosis among Polish pediatric patients

K Bąbol-Pokora, M Wołowiec, K Popko… - Archivum Immunologiae …, 2021 - Springer
Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome of life-threatening
inflammation caused by an excessive, prolonged and ineffective immune response. An …

[PDF][PDF] Hemophagocytic lymphohistiocytosis in Paediatric patients: A review

A Contino, G Trombatore, F Timeus - Journal of Blood Dissorders, 2018 - scientonline.org
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease due to a highly
stimulated but ineffective immune response, with uncontrolled proliferation of activated …

[HTML][HTML] Pediatric hemophagocytic lymphohistiocytosis: A rarely diagnosed entity in a developing country

D Cleves, V Lotero, D Medina, PM Perez, JA Patiño… - BMC pediatrics, 2021 - Springer
Background Hemophagocytic lymphohistiocytosis (HLH) is an exaggerated inflammatory
reaction secondary to a host's inadequate immune response causing a self-perpetuating …

Recent advances in diagnostic and therapeutic guidelines for primary and secondary hemophagocytic lymphohistiocytosis

S Ramachandran, F Zaidi, A Aggarwal… - Blood Cells, Molecules …, 2017 - Elsevier
Background Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome
characterized by excessive activation of macrophages and T cells resulting from defective …

A comprehensive analysis of adult patients with secondary hemophagocytic lymphohistiocytosis: a prospective cohort study

SE Yoon, Y Eun, K Huh, CR Chung, IY Yoo, J Cho… - Annals of …, 2020 - Springer
Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal condition with
various underlying disorders in adult patients and is diagnosed based on the HLH-2004 …

Gene mutation associated with hemophagocytic lymphohistiocytosis in children

K Chen, H LI, J LI, H Xiong - Journal of Clinical Pediatrics, 2017 - pesquisa.bvsalud.org
Objectives To detect gene mutation associated with hemophagocytic lymphohistiocytosis
(HLH) and to identify mutation spectrum and clinical feature in HLH in children. Methods …

[HTML][HTML] Outcome of patients with primary and secondary hemophagocytic lymphohistiocytosis: A retrospective analysis from a tertiary care center

AM Abbasi, MU Shaikh, M Shariq, MS Arif, A Arshad… - Medicine, 2023 - journals.lww.com
Hemophagocytic lymphohistiocytosis (HLH) is a progressive and potentially life-threatening
disorder. It is classified into primary and secondary HLH. The objective of our study was to …

[HTML][HTML] Epidemiology and outcomes of neonatal hemophagocytic lymphohistiocytosis

N Balakumar, P Sendi, BR Totapally - Frontiers in Pediatrics, 2022 - frontiersin.org
Objectives Neonatal hemophagocytic lymphohistiocytosis (HLH) is a rare entity. The
objective of the study was to describe the prevalence, clinical characteristics, interventions …

[HTML][HTML] Hemophagocytic Lymphohistiocytosis: manifestation of an untamed immune system

NK Bagri - The Indian Journal of Pediatrics, 2020 - Springer
Hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory state secondary to
impaired cytotoxicity and resultant cytokine storm, presenting with fever, multi-organ failure …

Rare diseases presenting with hemophagocytic lymphohistiocytosis

H Kanegane, A Noguchi, Y Yamada… - Pediatrics …, 2023 - Wiley Online Library
Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal hyperinflammatory disorder
characterized by hypercytokinemia caused by excessive activation of cytotoxic T cells and …