Diabetes mellitus is one of the most rapidly growing health concerns in the developed world
due to the persistence of type 1 (insulin-deficient) diabetes and the dramatic increase in type …

Neuropathy will afflict over half of the approximately 350 million people worldwide who
currently suffer from diabetes and around one-third of diabetic patients with neuropathy will …

Abnormal sensations and pain are features of approximately 10% of all cases of diabetic
neuropathy and can cause marked diminution in the quality of life for these patients. The …

Pain is frequently the earliest and most problematic syndrome of distal peripheral
neuropathy (DPN) in diabetic patients. The variety of time of onset, duration and …

They sought it with thimbles, they sought it with care; They pursued it with forks and hope;
They threatened its life with a railway-share; They charmed it with smiles and soap.(Lewis …

Diabetic peripheral neuropathy (DPN) is the most common clinical complication of diabetes
mellitus, and can be related to type 1 as well as type 2. To date, this highly invalidating …

Rational treatment of diabetic polyneuropathy depends upon establishing its cause, which is
at present unknown. A number of animal models of diabetes have been examined and …

Neuropathic pain is a common phenomenon resulting from injury to the central or peripheral
nervous system. The means by which diabetes results in nerve injury is unclear but the effect …

Diabetic neuropathy is a common complication of diabetes. It occurs in approximately 10–
20% of patients with diabetes, or roughly 40–50% patients with diabetic neuropathy …

Recent advances in understanding the pain associated with diabetic neuropathy are likely to
provide significant mechanistic insights and offer better therapies. In clinical research, new …