Seasonal influenza has a significant impact on global public health each year, especially in
older adults 65 years of age and above. This paper presents the evolution of high-dose …

Vaccination is the most practical means available for preventing influenza. Influenza
vaccines require frequent updates to keep pace with antigenic drift of the virus, and the …

Seasonal influenza remains a major public health problem, responsible for hundreds of
thousands of deaths every year, mostly of elderly people. Despite the wide availability of …

Influenza is associated with a substantial health burden, especially in high-risk subjects
such as older adults, frail individuals and those with underlying chronic diseases. In this …

Influenza can lead to serious illness, particularly for older adults. In addition to short-term
morbidity and mortality during the acute infection, recovery can be prolonged and often …

Foremost amongst the diseases preventable by vaccination is influenza. Worldwide,
influenza virus infection is associated with serious adverse events leading to hospitalization …

The main public health strategy for containing influenza-related disease is annual
vaccination, which is recommended for the elderly and others belonging to risk-factor …

Introduction Older adults are prioritized for influenza vaccination but also have lowered
antibody responses to the vaccine. Higher-doses of influenza antigen may increase immune …

Seasonal influenza is an acute syndrome, principally involving the respiratory tract caused
by influenza viruses that are globally present. Every year, influenza is responsible for an …

Influenza is foremost among all infectious diseases for an age-related increase in risk for
serious complications and death. Determining the benefit of current influenza vaccines is …