Results Most plasma amino acid concentrations were decreased in hemodialysis patients,
whereas proline, citrulline, asparagine, asymmetric dimethylarginine, and …

OBJECTIVE Patients with type 1 diabetes (T1D) with impaired renal function are at
increased risk for end-stage renal disease (ESRD). Although the rate of progression varies …

The prevalence of chronic kidney disease (CKD) is increasing and frequently progresses to
end-stage renal disease. There is an urgent demand to discover novel markers of disease …

Aims/hypothesis This prospective, observational study examines associations between 51
urinary metabolites and risk of progression of diabetic nephropathy in individuals with type 1 …

Background: Whereas several longitudinal metabolomics studies have been conducted in
individuals with normal estimated glomerular filtration rate (eGFR) at baseline, disease …

Here we studied plasma metabolomic profiles as determinants of progression to end-stage
renal disease (ESRD) in patients with type 2 diabetes (T2D). This nested case–control study …

The discovery of metabolomics-based biomarkers has been a focus of recent kidney
dysfunction research. In the present study, we aimed to identify metabolites associated with …

Results In the AASK and the MDRD study, respectively, the median urine protein-to-
creatinine ratio was 80 (interquartile range [IQR], 28–359) and 188 (IQR, 54–894) mg/g …

Plasma and muscle free amino acids in maintenance hemodialysis patients without protein
malnutrition. To investigate how uremia modified by maintenance hemodialysis treatment …

The progressive loss of kidney function in patients with chronic kidney disease (CKD) is
associated with a number of complications, including cardiovascular diseases, anemia …