[HTML][HTML] Donor mesenchymal stem cell-derived neural-like cells transdifferentiate into myelin-forming cells and promote axon regeneration in rat spinal cord …

XC Qiu, H Jin, RY Zhang, Y Ding, X Zeng… - Stem cell research & …, 2015 - Springer
Introduction Severe spinal cord injury often causes temporary or permanent damages in
strength, sensation, or autonomic functions below the site of the injury. So far, there is still no …

Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection

X Zeng, XC Qiu, YH Ma, JJ Duan, YF Chen, HY Gu… - Biomaterials, 2015 - Elsevier
Functional deficits following spinal cord injury (SCI) primarily attribute to loss of neural
connectivity. We therefore tested if novel tissue engineering approaches could enable …

Graft of a tissue-engineered neural scaffold serves as a promising strategy to restore myelination after rat spinal cord transection

BQ Lai, JM Wang, EA Ling, JL Wu… - Stem cells and …, 2014 - liebertpub.com
Remyelination remains a challenging issue in spinal cord injury (SCI). In the present study,
we cocultured Schwann cells (SCs) and neural stem cells (NSCs) with overexpression of …

Bone marrow stromal cells combined with a honeycomb collagen sponge facilitate neurite elongation in vitro and neural restoration in the hemisected rat spinal cord

M Onuma-Ukegawa, K Bhatt, T Hirai… - Cell …, 2015 - journals.sagepub.com
In the last decade, researchers and clinicians have reported that transplantation of bone
marrow stromal cells (BMSCs) promotes functional recovery after brain or spinal cord injury …

[HTML][HTML] Transplantation of bone marrow stromal cells enhances infiltration and survival of CNP and Schwann cells to promote axonal sprouting following complete …

P Ding, Z Yang, W Wang, J Wang… - American Journal of …, 2014 - ncbi.nlm.nih.gov
This study aimed to investigate the roles of bone marrow stromal cells (BMSCs) in promoting
axonal regeneration after complete transection of spinal cord in adult rats. Transplantation …

Acellular spinal cord scaffold seeded with bone marrow stromal cells protects tissue and promotes functional recovery in spinal cord‐injured rats

J Chen, Z Zhang, J Liu, R Zhou, X Zheng… - Journal of …, 2014 - Wiley Online Library
Therapy using scaffolds seeded with stem cells plays an important role in repair of spinal
cord injury (SCI), with the transplanted cells differentiating into nerve cells to replace the lost …

Enhanced axonal regeneration by transplanted Wnt3a-secreting human mesenchymal stem cells in a rat model of spinal cord injury

DK Seo, JH Kim, J Min, HH Yoon, ES Shin, SW Kim… - Acta …, 2017 - Springer
Background While pure mesenchymal stem cell (MSC) treatment for spinal cord injury (SCI)
is known to be safe, its efficacy is insufficient. Therefore, gene-modified stem cells are being …

Chronic spinal cord lesions respond positively to tranplants of mesenchymal stem cells

FM de Almeida, SA Marques… - Restorative …, 2015 - content.iospress.com
Purpose: Despite substantial advances in surgical care and rehabilitation, the
consequences of spinal cord injury (SCI) continue to present major challenges. Here we …

Transplanted adult spinal cord–derived neural stem/progenitor cells promote early functional recovery after rat spinal cord injury

AM Parr, I Kulbatski, T Zahir, X Wang, C Yue, A Keating… - Neuroscience, 2008 - Elsevier
We examined the effect of spinal cord–derived neural stem/progenitor cells (NSPCs) after
delayed transplantation into the injured adult rat spinal cord with or without earlier …

[HTML][HTML] Transplantation of rat cranial bone-derived mesenchymal stem cells promotes functional recovery in rats with spinal cord injury

Y Maeda, T Otsuka, M Takeda, T Okazaki, K Shimizu… - Scientific reports, 2021 - nature.com
Cell-based therapy using mesenchymal stem cells (MSCs) is a novel treatment strategy for
spinal cord injury (SCI). MSCs can be isolated from various tissues, and their characteristics …