Bone marrow mesenchymal stem cells (BMSCs) improved functional recovery of spinal cord injury partly by promoting axonal regeneration

L Lin, H Lin, S Bai, L Zheng, X Zhang - Neurochemistry international, 2018 - Elsevier
Spinal cord injury (SCI) disrupts the spinal cord and results in the loss of sensory and motor
function below the lesion site. The treatment of SCI became a challenge because the injured …

Human umbilical cord blood‐derived mesenchymal stem cell therapy promotes functional recovery of contused rat spinal cord through enhancement of endogenous …

SI Park, JY Lim, CH Jeong, SM Kim… - BioMed Research …, 2012 - Wiley Online Library
Numerous studies have shown the benefits of mesenchymal stem cells (MSCs) on the repair
of spinal cord injury (SCI) model and on behavioral improvement, but the underlying …

Acellular spinal cord scaffold seeded with mesenchymal stem cells promotes long-distance axon regeneration and functional recovery in spinal cord injured rats

J Liu, J Chen, B Liu, C Yang, D Xie, X Zheng… - Journal of the …, 2013 - Elsevier
The stem cell-based experimental therapies are partially successful for the recovery of
spinal cord injury (SCI). Recently, acellular spinal cord (ASC) scaffolds which mimic native …

Genetic modification of mesenchymal stem cells in spinal cord injury repair strategies

X Cui, L Chen, Y Ren, Y Ji, W Liu, J Liu, Q Yan… - BioScience …, 2013 - jstage.jst.go.jp
Spinal cord injury (SCI) is a serious injury of the central nervous system and up until now
there is no evident effective treatment for SCI. Axonal regeneration is the only way to restore …

Reduction of cystic cavity, promotion of axonal regeneration and sparing, and functional recovery with transplanted bone marrow stromal cell–derived Schwann cells …

Y Someya, M Koda, M Dezawa, T Kadota… - … of Neurosurgery: Spine, 2008 - thejns.org
Object The authors previously reported that Schwann cells (SCs) could be derived from
bone marrow stromal cells (BMSCs) in vitro and that they promoted axonal regeneration of …

Transplantation of bone marrow stromal cell-derived Schwann cells promotes axonal regeneration and functional recovery after complete transection of adult rat …

T Kamada, M Koda, M Dezawa… - … of Neuropathology & …, 2005 - academic.oup.com
The aim of this study was to evaluate whether transplantation of Schwann cells derived from
bone marrow stromal cells (BMSC-SCs) promotes axonal regeneration and functional …

The superiority of conditioned medium derived from rapidly expanded mesenchymal stem cells for neural repair

YT Chen, MJ Tsai, N Hsieh, MJ Lo, MJ Lee… - Stem Cell Research & …, 2019 - Springer
Abstracts Background Spinal cord injury (SCI) is a complex and severe neurological
condition. Mesenchymal stem cells (MSCs) and their secreted factors show promising …

Training neural stem cells on functional collagen scaffolds for severe spinal cord injury repair

X Li, S Liu, Y Zhao, J Li, W Ding, S Han… - Advanced functional …, 2016 - Wiley Online Library
Neural stem cells (NSCs) transplantation is regarded as a promising therapeutic strategy to
treat severe spinal cord injury (SCI) by compensating the neuronal loss. However, significant …

Functional recovery after rhesus monkey spinal cord injury by transplantation of bone marrow mesenchymal-stem cell-derived neurons

Y Deng, Q Yuan, X Liu, X Liu, Y Liu, Z Liu… - Chinese medical …, 2005 - mednexus.org
Background The treatment of spinal cord injury is still a challenge. This study aimed at
evaluating the therapeutical effectiveness of neurons derived form mesenchymal stem cells …

Implantation of BM mesenchymal stem cells into injured spinal cord elicits de novo neurogenesis and functional recovery: evidence from a study in rhesus monkeys

YB Deng, XG Liu, ZG Liu, XL Liu, Y Liu, GQ Zhou - Cytotherapy, 2006 - Taylor & Francis
Background Transplantation of mesenchymal stem cells (MSC) in rodent models has proved
to be an effective therapeutic approach for spinal cord injury (SCI). However, further studies …