Neural stem cells for spinal cord repair

B Sandner, P Prang, FJ Rivera, L Aigner, A Blesch… - Cell and tissue …, 2012 - Springer
Spinal cord injury (SCI) causes the irreversible loss of spinal cord parenchyma including
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …

Transplanted bone marrow stromal cells promote axonal regeneration and improve motor function in a rat spinal cord injury model

Y Chiba, S Kuroda, K Maruichi, T Osanai, M Hokari… - …, 2009 - journals.lww.com
OBJECTIVE: Recent studies have indicated that bone marrow stromal cells (BMSCs) have
the potential to improve neurological function when transplanted into animal models of …

Transplantation of a combination of autologous neural differentiated and undifferentiated mesenchymal stem cells into injured spinal cord of rats

MS Pedram, MM Dehghan, M Soleimani, D Sharifi… - Spinal Cord, 2010 - nature.com
Study design: The use of stem cells for functional recovery after spinal cord injury. Objective:
The aim of this study was to evaluate the effects of a combination of autologous …

Stem cell-based cell therapy for spinal cord injury

BG Kim, DH Hwang, SI Lee, EJ Kim… - Cell …, 2007 - journals.sagepub.com
Traumatic injuries to the spinal cord lead to severe and permanent neurological deficits.
Although no effective therapeutic option is currently available, recent animal studies have …

Conditioned medium from bone marrow-derived mesenchymal stem cells improves recovery after spinal cord injury in rats: an original strategy to avoid cell …

D Cantinieaux, R Quertainmont, S Blacher, L Rossi… - PloS one, 2013 - journals.plos.org
Spinal cord injury triggers irreversible loss of motor and sensory functions. Numerous
strategies aiming at repairing the injured spinal cord have been studied. Among them, the …

Transplantation of mesenchymal stem cells enhances axonal outgrowth and cell survival in an organotypic spinal cord slice culture

JS Cho, HW Park, SK Park, S Roh, SK Kang, KS Paik… - Neuroscience …, 2009 - Elsevier
Mesenchymal stem cells (MSCs) have demonstrated a measurable therapeutic effect
following transplantation into animal models of spinal cord injury. However, the mechanism …

Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome

M Osaka, O Honmou, T Murakami, T Nonaka, K Houkin… - Brain research, 2010 - Elsevier
Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been
shown to improve functional outcome in spinal cord injury (SCI). Systemic delivery of MSCs …

Concomitant use of mesenchymal stem cells and neural stem cells for treatment of spinal cord injury: a combo cell therapy approach

SM Hosseini, M Sani, KH Haider, M Dorvash… - Neuroscience …, 2018 - Elsevier
Abstract Treatment: with neural stem cells (NSCs) provides a hope to recover the neural
damage and compensate for the lost neural structures for restoration of interrupted neural …

Therapeutic potential of induced neural stem cells for spinal cord injury

JY Hong, SH Lee, SC Lee, JW Kim, KP Kim… - Journal of Biological …, 2014 - ASBMB
The spinal cord does not spontaneously regenerate, and treatment that ensures functional
recovery after spinal cord injury (SCI) is still not available. Recently, fibroblasts have been …

Bone marrow–derived mesenchymal stem cell transplantation for chronic spinal cord injury in rats: comparative study between intralesional and intravenous …

JW Kim, KY Ha, JN Molon, YH Kim - Spine, 2013 - journals.lww.com
Study Design. Animal experimental study. Objective. To present experimental evidence for
mesenchymal cell therapy for spinal cord injury (SCI). Summary of Background Data. Prior to …