Neural stem cells for spinal cord repair
Spinal cord injury (SCI) causes the irreversible loss of spinal cord parenchyma including
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …
astroglia, oligodendroglia and neurons. In particular, severe injuries can lead to an almost …
Transplanted bone marrow stromal cells promote axonal regeneration and improve motor function in a rat spinal cord injury model
Y Chiba, S Kuroda, K Maruichi, T Osanai, M Hokari… - …, 2009 - journals.lww.com
OBJECTIVE: Recent studies have indicated that bone marrow stromal cells (BMSCs) have
the potential to improve neurological function when transplanted into animal models of …
the potential to improve neurological function when transplanted into animal models of …
Transplantation of a combination of autologous neural differentiated and undifferentiated mesenchymal stem cells into injured spinal cord of rats
Study design: The use of stem cells for functional recovery after spinal cord injury. Objective:
The aim of this study was to evaluate the effects of a combination of autologous …
The aim of this study was to evaluate the effects of a combination of autologous …
Stem cell-based cell therapy for spinal cord injury
BG Kim, DH Hwang, SI Lee, EJ Kim… - Cell …, 2007 - journals.sagepub.com
Traumatic injuries to the spinal cord lead to severe and permanent neurological deficits.
Although no effective therapeutic option is currently available, recent animal studies have …
Although no effective therapeutic option is currently available, recent animal studies have …
Conditioned medium from bone marrow-derived mesenchymal stem cells improves recovery after spinal cord injury in rats: an original strategy to avoid cell …
D Cantinieaux, R Quertainmont, S Blacher, L Rossi… - PloS one, 2013 - journals.plos.org
Spinal cord injury triggers irreversible loss of motor and sensory functions. Numerous
strategies aiming at repairing the injured spinal cord have been studied. Among them, the …
strategies aiming at repairing the injured spinal cord have been studied. Among them, the …
Transplantation of mesenchymal stem cells enhances axonal outgrowth and cell survival in an organotypic spinal cord slice culture
Mesenchymal stem cells (MSCs) have demonstrated a measurable therapeutic effect
following transplantation into animal models of spinal cord injury. However, the mechanism …
following transplantation into animal models of spinal cord injury. However, the mechanism …
Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome
M Osaka, O Honmou, T Murakami, T Nonaka, K Houkin… - Brain research, 2010 - Elsevier
Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been
shown to improve functional outcome in spinal cord injury (SCI). Systemic delivery of MSCs …
shown to improve functional outcome in spinal cord injury (SCI). Systemic delivery of MSCs …
Concomitant use of mesenchymal stem cells and neural stem cells for treatment of spinal cord injury: a combo cell therapy approach
Abstract Treatment: with neural stem cells (NSCs) provides a hope to recover the neural
damage and compensate for the lost neural structures for restoration of interrupted neural …
damage and compensate for the lost neural structures for restoration of interrupted neural …
Therapeutic potential of induced neural stem cells for spinal cord injury
JY Hong, SH Lee, SC Lee, JW Kim, KP Kim… - Journal of Biological …, 2014 - ASBMB
The spinal cord does not spontaneously regenerate, and treatment that ensures functional
recovery after spinal cord injury (SCI) is still not available. Recently, fibroblasts have been …
recovery after spinal cord injury (SCI) is still not available. Recently, fibroblasts have been …
Bone marrow–derived mesenchymal stem cell transplantation for chronic spinal cord injury in rats: comparative study between intralesional and intravenous …
JW Kim, KY Ha, JN Molon, YH Kim - Spine, 2013 - journals.lww.com
Study Design. Animal experimental study. Objective. To present experimental evidence for
mesenchymal cell therapy for spinal cord injury (SCI). Summary of Background Data. Prior to …
mesenchymal cell therapy for spinal cord injury (SCI). Summary of Background Data. Prior to …