Transplantation of human skin-derived mesenchymal stromal cells improves locomotor recovery after spinal cord injury in rats

FR Melo, RB Bressan, S Forner, AC Martini… - Cellular and molecular …, 2017 - Springer
Spinal cord injury (SCI) is a devastating neurologic disorder with significant impacts on
quality of life, life expectancy, and economic burden. Although there are no fully restorative …

Improved stem cell therapy of spinal cord injury using GDNF-overexpressed bone marrow stem cells in a rat model

M Shahrezaie, RN Mansour, B Nazari, H Hassannia… - Biologicals, 2017 - Elsevier
The use of stem cell base therapy as an effective strategy for the treatment of spinal cord
injury (SCI) is very promising. Although some strategy has been made to generate neural …

[HTML][HTML] Role of bone marrow derived mesenchymal stromal cells and Schwann-like cells transplantation on spinal cord injury in adult male albino rats

RA Galhom, HHH Abd El Raouf, MHM Ali - Biomedicine & …, 2018 - Elsevier
Background Spinal cord injury is a considerable health impact accompanied with physical,
psychological and economic burden. Bone marrow derived mesenchymal stromal cells (BM …

Effects of human mesenchymal stem cell transplantation combined with polymer on functional recovery following spinal cord hemisection in rats

JS Choi, JW Leem, KH Lee, SS Kim… - The Korean Journal …, 2012 - synapse.koreamed.org
The spontaneous axon regeneration of damaged neurons is limited after spinal cord injury
(SCI). Recently, mesenchymal stem cell (MSC) transplantation was proposed as a potential …

[HTML][HTML] Engineered human spinal cord-like tissues with dorsal and ventral neuronal progenitors for spinal cord injury repair in rats and monkeys

B Xu, D Liu, W Liu, G Long, W Liu, Y Wu, X He, Y Shen… - Bioactive Materials, 2023 - Elsevier
Transplanting human neural progenitor cells is a promising method of replenishing the lost
neurons after spinal cord injury (SCI), but differentiating neural progenitor cells into the …

BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury

M Sasaki, C Radtke, AM Tan, P Zhao… - Journal of …, 2009 - Soc Neuroscience
Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been
shown to improve functional outcome in spinal cord injury (SCI). We transplanted MSCs …

Motor recovery after transplantation of bone marrow mesenchymal stem cells in rat models of spinal cord injury

DM Muniswami, P Kanthakumar… - Annals of …, 2019 - karger.com
Background: Neuronal tissue has a limited potential to self-renew or get repaired after
damage. Cell therapies using stem cells are promising approaches for the treatment of …

Bone marrow stromal cells promote neurite extension in organotypic spinal cord slice: significance for cell transplantation therapy

H Shichinohe, S Kuroda, S Tsuji… - … and Neural Repair, 2008 - journals.sagepub.com
Objective. Recent reports have indicated that bone marrow stromal cells (BMSCs) have the
potential to improve neurological function when transplanted into models of central nervous …

Collagen scaffold combined with human umbilical cord-mesenchymal stem cells transplantation for acute complete spinal cord injury

WS Deng, K Ma, B Liang, XY Liu, HY Xu… - Neural Regeneration …, 2020 - journals.lww.com
Currently, there is no effective strategy to promote functional recovery after a spinal cord
injury. Collagen scaffolds can not only provide support and guidance for axonal …

Treatment of spinal cord injury with mesenchymal stem cells

LL Liau, QH Looi, WC Chia, T Subramaniam, MH Ng… - Cell & bioscience, 2020 - Springer
Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to
temporary or permanent loss of function due to injury to the nerve. The SCI patients are often …