Kaempferol induced the apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 cells
EJ Choi, WS Ahn - Nutrition research and practice, 2008 - synapse.koreamed.org
The aim of present study was to investigate the effects of kaempferol on cellular proliferation
and cell cycle arrest and explore the mechanism for these effects in human breast …
and cell cycle arrest and explore the mechanism for these effects in human breast …
[HTML][HTML] Kaempferol suppresses proliferation and induces cell cycle arrest, apoptosis, and DNA damage in breast cancer cells
L Zhu, L Xue - Oncology research, 2019 - ncbi.nlm.nih.gov
Kaempferol is a flavonoid that has been extensively investigated owing to its antitumor
effects. Nevertheless, little is known about its underlying mechanisms of action. We aimed to …
effects. Nevertheless, little is known about its underlying mechanisms of action. We aimed to …
Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells
HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
Kaempferol inhibits gastric cancer tumor growth: An in vitro and in vivo study
H Song, J Bao, Y Wei, Y Chen, X Mao… - Oncology …, 2015 - spandidos-publications.com
Kaempferol, which is one of the general flavonoids, has recently been reported to suppress
proliferation, induce cell cycle arrest and promote apoptosis in various human cancer cell …
proliferation, induce cell cycle arrest and promote apoptosis in various human cancer cell …
Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti‐
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …
Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway
H Luo, GO Rankin, Z Li, L DePriest, YC Chen - Food Chemistry, 2011 - Elsevier
Ovarian cancer is a significant malignancy for women in the Western world, and its death
rate has remained unchanged over the past 50 years, leaving room for proper …
rate has remained unchanged over the past 50 years, leaving room for proper …
Kaempferol induces G2/M cell cycle arrest via checkpoint kinase 2 and promotes apoptosis via death receptors in human ovarian carcinoma A2780/CP70 cells
Y Gao, J Yin, GO Rankin, YC Chen - Molecules, 2018 - mdpi.com
Kaempferol is a widely distributed dietary flavonoid. Epidemiological studies have
demonstrated kaempferol consumption lowers the risk of ovarian cancer. Our previous …
demonstrated kaempferol consumption lowers the risk of ovarian cancer. Our previous …
Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated …
W Li, B Du, T Wang, S Wang, J Zhang - Chemico-Biological Interactions, 2009 - Elsevier
Dietary flavonols have been found to possess preventive and therapeutic potential against
several kinds of cancers. This study is conducted to investigate the anti-proliferation effects …
several kinds of cancers. This study is conducted to investigate the anti-proliferation effects …
Anti-cancer effect and underlying mechanism (s) of kaempferol, a phytoestrogen, on the regulation of apoptosis in diverse cancer cell models
SH Kim, KC Choi - Toxicological research, 2013 - Springer
Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long
times, phytoestrogens have been used for therapeutic treatments against human diseases …
times, phytoestrogens have been used for therapeutic treatments against human diseases …
Reactive oxygen species and p53 mediated activation of p38 and caspases is critically involved in kaempferol induced apoptosis in colorectal cancer cells
Here the molecular mechanisms of Kaempferol were examined in colorectal cancers
(CRCs). Kaempferol significantly exerted antiproliferative and cytotoxic effect in HCT116 …
(CRCs). Kaempferol significantly exerted antiproliferative and cytotoxic effect in HCT116 …